Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TAT6 / NPL4_HUMAN
Protein Name Nuclear protein localization protein 4 homolog
Gene Name Name: NPLOC4
Synonyms:KIAA1499,NPL4;
Organism Homo sapiens (Human)

PRO ID PR:Q8TAT6
DAG View
PRO Name nuclear protein localization protein 4 homolog (human)
Definition A nuclear protein localization protein 4 that is encoded in the genome of human.
Short Label hNPLOC4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TAT6 (NPLOC4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
S4 Phosphorylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
K16 Ubiquitination PhosphoSitePlus
T21 Phosphorylation PhosphoSitePlus
T28 Phosphorylation PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
Y113 Phosphorylation PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
Y151 Phosphorylation PhosphoSitePlus
T172 Phosphorylation PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
C188 S-Nitrosylation dbSNO 19483679, 22178444
K189 Ubiquitination PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
Y251 Phosphorylation PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
Y274 Phosphorylation PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
K302 Ubiquitination PhosphoSitePlus
K307 Ubiquitination PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
S358 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
K427 Ubiquitination PhosphoSitePlus
K431 Ubiquitination PhosphoSitePlus
K544 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S11 Y11 Biomuta DOID:3571 / liver cancer [ icgc ]
K16 N16 Biomuta DOID:363 / uterine cancer [ tcga ]
K16 R16 Biomuta DOID:263 / kidney cancer [ tcga ]
K62 I62 Biomuta DOID:3571 / liver cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ]
K120 R120 Biomuta DOID:363 / uterine cancer [ tcga ]
K260 I260 Biomuta DOID:9256 / colorectal cancer [ icgc ] DOID:263 / kidney cancer [ cosmic ]