iPTMnet Report for Q8TAS1 (UHMK1)
Protein Information
| UniProt AC / UniProt ID | Q8TAS1 / UHMK1_HUMAN |
| Protein Name | Serine/threonine-protein kinase Kist |
| Gene Name | Name: UHMK1 Synonyms:KIS,KIST; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8TAS1 |
| PRO Name | serine/threonine-protein kinase Kist (human) |
| Definition | A serine/threonine-protein kinase Kist that is encoded in the genome of human. |
| Short Label | hUHMK1 |
| Category | organism-gene |
DAG ViewQ8TAS1 (UHMK1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K54 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C108 | Methylation | score1 | IEDB | 31844290 | ||
| K183 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K190 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y197 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C207 | Methylation | score1 | IEDB | 31844290 | ||
| K251 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K265 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K282 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S283 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S290 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K364 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K383 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K387 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K397 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K410 | Ubiquitination | score1 | PhosphoSitePlus |
Q8TAS1 (UHMK1) as PTM Enzyme
|
Substrate | Site | Score | Source | PMID |
|---|---|---|---|---|---|
| P02686 (MBP) | S299 | score2 | Signor | 10880969, 16401070 | |
| P16949 (STMN1) | S38 | score3 | PhosphoSitePlus Signor | 19033656 | |
| P17600 (SYN1) | S438 | score1 | Signor | 10880969 | |
| P19021-2 (PAM) | S839 | score2 | HPRD | 19651622, 10574929 | |
| P19021-4 (PAM) | S860 | score2 | HPRD | 19651622, 10574929 | |
| P19021-3 (PAM) | S878 | score2 | HPRD | 19651622, 10574929 | |
| P19021 (PAM) | S946 | score1 | Signor | 10574929 | |
| P19021-5 (PAM) | S947 | score2 | HPRD | 19651622, 10574929 | |
| P46527 (CDKN1B) | S10 | score4 | PhosphoSitePlus Signor | 10831586, 12093740 | |
| Q15637 (SF1) | S80 | score4 | PhosphoSitePlus Signor | 23175611, 16420481 | |
| Q15637 (SF1) | S82 | score4 | PhosphoSitePlus Signor | 23175611, 16420481 | |
| Q9BSJ6 (PIMREG) | S131 | score3 | PhosphoSitePlus Signor | 23419774 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C108 | Y108 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K183 | T183 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K410 | N410 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |
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