iPTMnet Report for Q8TAQ5 (ZNF420)
Protein Information
| UniProt AC / UniProt ID | Q8TAQ5 / ZN420_HUMAN |
| Protein Name | Zinc finger protein 420 |
| Gene Name | Name: ZNF420 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8TAQ5 |
| PRO Name | zinc finger protein 420 (human) |
| Definition | A zinc finger protein 420 that is encoded in the genome of human. |
| Short Label | hZNF420 |
| Category | organism-gene |
Q8TAQ5 (ZNF420) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| C22 | Methylation | score1 | IEDB | 31844290 | ||
| Y39 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S40 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S44 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S68 | Phosphorylation | score3 | PRO PhosphoSitePlus Signor | 19377469 | ||
| S68 | Phosphorylation | Q13315 (ATM) | score3 | PhosphoSitePlus Signor | 19377469 | |
| T162 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K170 | Sumoylation | score1 | PhosphoSitePlus | |||
| S180 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S183 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T190 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K198 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T218 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K221 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K224 | Sumoylation | score1 | PhosphoSitePlus | |||
| K224 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K230 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S236 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T246 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K249 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K254 | Sumoylation | score1 | PhosphoSitePlus | |||
| T274 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T302 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K310 | Sumoylation | score1 | PhosphoSitePlus | |||
| T358 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K361 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K364 | Sumoylation | score1 | PhosphoSitePlus | |||
| K364 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K370 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S376 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K394 | Sumoylation | score1 | PhosphoSitePlus | |||
| T414 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K422 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K426 | Acetylation | score1 | PhosphoSitePlus | |||
| T442 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K450 | Sumoylation | score1 | PhosphoSitePlus | |||
| T470 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K478 | Sumoylation | score1 | PhosphoSitePlus | |||
| S488 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17525332 | ||
| T498 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T526 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K529 | Sumoylation | score1 | PhosphoSitePlus | |||
| T554 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K562 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K566 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S572 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T582 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K590 | Sumoylation | score1 | PhosphoSitePlus | |||
| T610 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K622 | Sumoylation | score1 | PhosphoSitePlus | |||
| T638 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K646 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S656 | Phosphorylation | score1 | PhosphoSitePlus |
Proteoforms
| PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
|---|---|---|---|---|---|
| PR:000049727 (hZNF420/Phos:1) | pS68 | PRO |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C22 | S22 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| Y39 | C39 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
| S44 | L44 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S68 | F68 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| T302 | A302 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K361 | R361 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K361 | N361 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| K364 | Q364 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| K450 | E450 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S488 | A488 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K529 | N529 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K566 | T566 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| T638 | S638 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
DAG View