iPTMnet Report for Q8TAQ2 (SMARCC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TAQ2 / SMRC2_HUMAN
Protein Name SWI/SNF complex subunit SMARCC2
Gene Name Name: SMARCC2
Synonyms:BAF170;
Organism Homo sapiens (Human)

PRO ID PR:Q8TAQ2
DAG View
PRO Name SWI/SNF complex subunit SMARCC2 (human)
Definition A SWI/SNF complex subunit SMARCC2 that is encoded in the genome of human.
Short Label hSMARCC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TAQ2 (SMARCC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K37 Ubiquitination PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
C145 S-Nitrosylation dbSNO 20140087, 22178444
K157 Ubiquitination PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
Y179 Phosphorylation PhosphoSitePlus
T230 Phosphorylation PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
T276 Phosphorylation PhosphoSitePlus
S283 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 15302935, ...18669648, 24275569
S286 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Y296 Phosphorylation PhosphoSitePlus
S302 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 16083285, 23186163, ...15302935, 18669648, 20068231
S304 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 16083285, 15302935, ...18669648, 20068231
S306 Phosphorylation PhosphoSitePlus   UniProt 20068231
T308 Phosphorylation PhosphoSitePlus
S321 Phosphorylation PhosphoSitePlus
T322 Phosphorylation PhosphoSitePlus
Y324 Phosphorylation PhosphoSitePlus
K326 Acetylation PhosphoSitePlus   UniProt 19608861
S327 Phosphorylation PhosphoSitePlus
S347 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...15302935, 18669648, 24275569, 19690332, 20068231
S367 Phosphorylation PhosphoSitePlus
S369 Phosphorylation PhosphoSitePlus
T376 Phosphorylation PhosphoSitePlus
T378 Phosphorylation PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus
T390 Phosphorylation PhosphoSitePlus
S399 Phosphorylation PhosphoSitePlus
T400 Phosphorylation PhosphoSitePlus
K453 Ubiquitination PhosphoSitePlus
K457 Ubiquitination PhosphoSitePlus
C486 Methylation IEDB 31844290
T548 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S553 Phosphorylation PhosphoSitePlus
S555 Phosphorylation PhosphoSitePlus
K564 Ubiquitination PhosphoSitePlus
K566 Ubiquitination PhosphoSitePlus
K568 Ubiquitination PhosphoSitePlus
T579 Phosphorylation PhosphoSitePlus
Y582 Phosphorylation PhosphoSitePlus
T583 Phosphorylation PhosphoSitePlus
K592 Methylation PhosphoSitePlus
K622 Ubiquitination PhosphoSitePlus
C635 Methylation IEDB 31844290
C635 S-Nitrosylation dbSNO 26338901
K694 Ubiquitination PhosphoSitePlus
S695 Phosphorylation PhosphoSitePlus
K702 Ubiquitination PhosphoSitePlus
K704 Sumoylation PhosphoSitePlus
K704 Ubiquitination PhosphoSitePlus
K724 Ubiquitination PhosphoSitePlus
T726 Phosphorylation PhosphoSitePlus
K728 Ubiquitination PhosphoSitePlus
S738 Phosphorylation PhosphoSitePlus
S754 Phosphorylation PhosphoSitePlus
K769 Acetylation PhosphoSitePlus
K795 Acetylation PhosphoSitePlus
S806 Phosphorylation PhosphoSitePlus
S810 Phosphorylation PhosphoSitePlus
S813 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
K836 Ubiquitination PhosphoSitePlus
S841 Phosphorylation PhosphoSitePlus
K872 Ubiquitination PhosphoSitePlus
K874 Ubiquitination PhosphoSitePlus
K885 Ubiquitination PhosphoSitePlus
S886 Phosphorylation PhosphoSitePlus
K897 Ubiquitination PhosphoSitePlus
K898 Ubiquitination PhosphoSitePlus
K902 Ubiquitination PhosphoSitePlus
R931 Methylation PhosphoSitePlus
K940 Ubiquitination PhosphoSitePlus
S969 Phosphorylation Q13315 (ATM) , Q13535 (ATR) neXtProt   PhosphoSitePlus 19525936
Site PTM Type PTM Enzyme Score Source PMID
S102 Phosphorylation HPRD 20068231
S283 Phosphorylation HPRD 17322306, 19664994, 19664995, ...18452278, 19651622, 18669648, 20068231, 19691289
S286 Phosphorylation HPRD 19664995, 17081983, 19691289, ...18452278, 19651622, 18669648, 20068231
Y296 Phosphorylation HPRD 17924679
S302 Phosphorylation HPRD 19413330, 15302935, 19691289, ...19651622, 18669648, 18707149, 20166139, 20068231
S304 Phosphorylation HPRD 19413330, 15302935, 19007248, ...19651622, 18669648, 18707149, 20166139, 20068231
S306 Phosphorylation HPRD 19413330, 19651622, 20166139, ...20068231, 17081983
T308 Phosphorylation HPRD 19651622, 17081983, 20068231
S321 Phosphorylation HPRD 19664995
T322 Phosphorylation HPRD 17924679
S347 Phosphorylation HPRD 19413330, 17322306, 20058876, ...19664995, 18452278, 19651622, 18669648, 20068231, 19691289
S399 Phosphorylation HPRD 18452278
Y465 Phosphorylation HPRD 20068231
T548 Phosphorylation HPRD 18669648, 20068231
S806 Phosphorylation HPRD 18452278
S810 Phosphorylation HPRD 18452278
S813 Phosphorylation HPRD 19651622, 20068231, 18452278
S841 Phosphorylation HPRD 20068231
T1208 Phosphorylation HPRD 17081983
Site PTM Type PTM Enzyme Score Source PMID
S102 Phosphorylation HPRD 20068231
S283 Phosphorylation HPRD 17322306, 19664994, 19664995, ...18452278, 19651622, 18669648, 20068231, 19691289
S286 Phosphorylation HPRD 19664995, 17081983, 19691289, ...18452278, 19651622, 18669648, 20068231
Y296 Phosphorylation HPRD 17924679
S302 Phosphorylation HPRD 19413330, 15302935, 19691289, ...19651622, 18669648, 18707149, 20166139, 20068231
S304 Phosphorylation HPRD 19413330, 15302935, 19007248, ...19651622, 18669648, 18707149, 20166139, 20068231
S306 Phosphorylation HPRD 19413330, 19651622, 20166139, ...20068231, 17081983
T308 Phosphorylation HPRD 19651622, 17081983, 20068231
S321 Phosphorylation HPRD 19664995
T322 Phosphorylation HPRD 17924679
S347 Phosphorylation HPRD 19413330, 17322306, 20058876, ...19664995, 18452278, 19651622, 18669648, 20068231, 19691289
S399 Phosphorylation HPRD 18452278
Y465 Phosphorylation HPRD 20068231
S586 Phosphorylation PhosphoSitePlus
S837 Phosphorylation HPRD 18452278
S841 Phosphorylation HPRD 18452278
S844 Phosphorylation HPRD 19651622, 20068231, 18452278
S872 Phosphorylation HPRD 20068231
T1124 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K161 N161 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S304 C304 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S306 L306 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S321 L321 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S367 * Biomuta DOID:4362 / cervical cancer [ cosmic ]
S369 L369 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T390 M390 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
T400 M400 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y465 H465 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S553 F553 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K622 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K622 N622 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
C635 W635 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K795 T795 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K836 N836 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K874 N874 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S886 F886 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K902 E902 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S969 F969 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc, cosmic, icgc ]