iPTMnet Report for Q8TAP6 (CEP76)
Protein Information
UniProt AC / UniProt ID | Q8TAP6 / CEP76_HUMAN |
Protein Name | Centrosomal protein of 76 kDa |
Gene Name | Name: CEP76 Synonyms:C18orf9; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8TAP6 |
PRO Name | centrosomal protein of 76 kDa (human) |
Definition | A centrosomal protein of 76 kDa that is encoded in the genome of human. |
Short Label | hCEP76 |
Category | organism-gene |
Q8TAP6 (CEP76) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S9 | Phosphorylation | score1 | PhosphoSitePlus | |||
K12 | Ubiquitination | score1 | PhosphoSitePlus | |||
K21 | Ubiquitination | score1 | PhosphoSitePlus | |||
K54 | Ubiquitination | score1 | PhosphoSitePlus | |||
S82 | Phosphorylation | score1 | PhosphoSitePlus | |||
S83 | Phosphorylation | P24941 (CDK2) | score4 | phospho.ELM PhosphoSitePlus RLIMS-P+ UniProt | 27065328, 18669648, 19690332 | |
K85 | Ubiquitination | score1 | PhosphoSitePlus | |||
S94 | Phosphorylation | score1 | PhosphoSitePlus | |||
T95 | Phosphorylation | score1 | PhosphoSitePlus | |||
C139 | Methylation | score1 | IEDB | 31844290 | ||
K279 | Acetylation | score1 | PhosphoSitePlus | |||
S322 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y323 | Phosphorylation | score1 | PhosphoSitePlus | |||
K325 | Ubiquitination | score1 | PhosphoSitePlus | |||
K434 | Ubiquitination | score1 | PhosphoSitePlus | |||
K489 | Ubiquitination | score1 | PhosphoSitePlus | |||
S537 | Phosphorylation | score1 | PhosphoSitePlus | |||
K594 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S83 | C83 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
C139 | Y139 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S322 | F322 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K434 | T434 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] |