iPTMnet Report for Q8TAG9 (EXOC6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TAG9 / EXOC6_HUMAN
Protein Name Exocyst complex component 6
Gene Name Name: EXOC6
Synonyms:SEC15A,SEC15L,SEC15L1;
Organism Homo sapiens (Human)

PRO ID PR:Q8TAG9
DAG View
PRO Name exocyst complex component 6 (human)
Definition An exocyst complex component 6 that is encoded in the genome of human.
Short Label hEXOC6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TAG9 (EXOC6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
C28 Methylation IEDB 31844290
C28 S-Nitrosylation dbSNO 26338901
K91 Ubiquitination PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
Y155 Phosphorylation PhosphoSitePlus
Y175 Phosphorylation PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
K220 Methylation PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
T301 Phosphorylation PhosphoSitePlus
S446 Phosphorylation PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
K472 Ubiquitination PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus
S505 Phosphorylation PhosphoSitePlus
K519 Ubiquitination PhosphoSitePlus
T545 Phosphorylation IEDB 35494241
K591 Ubiquitination PhosphoSitePlus
K604 Ubiquitination PhosphoSitePlus
K608 Ubiquitination PhosphoSitePlus
K791 Ubiquitination PhosphoSitePlus
S801 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K91 T91 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y155 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S196 T196 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S196 F196 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S198 C198 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K201 N201 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K213 N213 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S801 Y801 Biomuta DOID:1612 / breast cancer [ cosmic ]