iPTMnet Report for Q8TAF7 (ZNF461)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TAF7 / ZN461_HUMAN
Protein Name Zinc finger protein 461
Gene Name Name: ZNF461
Synonyms:GIOT1;
Organism Homo sapiens (Human)

PRO ID PR:Q8TAF7
DAG View
PRO Name zinc finger protein 461 (human)
Definition A zinc finger protein 461 that is encoded in the genome of human.
Short Label hZNF461
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TAF7 (ZNF461) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y39 Phosphorylation PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus
T296 Phosphorylation PhosphoSitePlus
K304 Sumoylation PhosphoSitePlus
T324 Phosphorylation PhosphoSitePlus
K327 Sumoylation PhosphoSitePlus
K327 Ubiquitination PhosphoSitePlus
K332 Sumoylation PhosphoSitePlus
T345 Phosphorylation PhosphoSitePlus
T352 Phosphorylation PhosphoSitePlus
K355 Sumoylation PhosphoSitePlus
K355 Ubiquitination PhosphoSitePlus
K360 Sumoylation PhosphoSitePlus
K360 Ubiquitination PhosphoSitePlus
T380 Phosphorylation PhosphoSitePlus
T436 Phosphorylation PhosphoSitePlus
K444 Sumoylation PhosphoSitePlus
T492 Phosphorylation PhosphoSitePlus
K500 Sumoylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y39 H39 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S112 Y112 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ icgc ] DOID:11934 / head and neck cancer [ icgc ]
T296 A296 Biomuta DOID:363 / uterine cancer [ icgc ]
K327 N327 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K327 T327 Biomuta DOID:363 / uterine cancer [ icgc ]
K332 N332 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K360 E360 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K500 Q500 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
K500 R500 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]