iPTMnet Report for Q8TAF3 (WDR48)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TAF3 / WDR48_HUMAN
Protein Name WD repeat-containing protein 48
Gene Name Name: WDR48
Synonyms:KIAA1449;
Organism Homo sapiens (Human)

PRO ID PR:Q8TAF3
DAG View
PRO Name WD repeat-containing protein 48 (human)
Definition A WD repeat-containing protein 48 that is encoded in the genome of human.
Short Label hWDR48
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TAF3 (WDR48) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K106 Ubiquitination PhosphoSitePlus
K121 Acetylation PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
K214 Acetylation PhosphoSitePlus   UniProt 19608861
C244 Methylation IEDB 31844290
K275 Ubiquitination PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
K318 Ubiquitination PhosphoSitePlus
K327 Ubiquitination PhosphoSitePlus
S335 Phosphorylation PhosphoSitePlus
Y338 Phosphorylation PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
T377 Phosphorylation PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
K391 Ubiquitination PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
K408 Ubiquitination PhosphoSitePlus
S451 Phosphorylation PhosphoSitePlus
S452 Phosphorylation PhosphoSitePlus
S456 Phosphorylation PhosphoSitePlus
Y568 Phosphorylation PhosphoSitePlus
S575 Phosphorylation PhosphoSitePlus
K578 Acetylation PhosphoSitePlus
K578 Ubiquitination PhosphoSitePlus
S586 Phosphorylation PhosphoSitePlus
S611 Phosphorylation PhosphoSitePlus
T613 Phosphorylation PhosphoSitePlus   UniProt 24275569
K621 Ubiquitination PhosphoSitePlus
S664 Phosphorylation PhosphoSitePlus
Y672 Phosphorylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O94782 (USP1) S313 Q8TAF3 (WDR48) unknown eFIP 25744535
Phosphorylation O94782 (USP1) S313 Q8TAF3 (WDR48) unknown eFIP 23116119


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K106 R106 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K106 N106 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
S305 L305 Biomuta DOID:1324 / lung cancer [ cosmic ]
S456 L456 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]