iPTMnet Report for Q8TAA9 (VANGL1)
Protein Information
| UniProt AC / UniProt ID | Q8TAA9 / VANG1_HUMAN |
| Protein Name | Vang-like protein 1 |
| Gene Name | Name: VANGL1 Synonyms:STB2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8TAA9 |
| PRO Name | Vang-like protein 1 (human) |
| Definition | A Vang-like protein 1 that is encoded in the genome of human. |
| Short Label | hVANGL1 |
| Category | organism-gene |
Q8TAA9 (VANGL1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Y7 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y13 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S20 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S42 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| K44 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S45 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| T52 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
| S83 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S86 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S88 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S96 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K97 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T288 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y290 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T296 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K299 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K304 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K310 | Acetylation | score1 | PhosphoSitePlus | |||
| K310 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y312 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S325 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S338 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S339 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y344 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y345 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K382 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K407 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K455 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K513 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S520 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T522 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S523 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S42 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S45 | Phosphorylation | score0 | HPRD | 18669648 | ||
| T52 | Phosphorylation | score0 | HPRD | 18669648 | ||
| T80 | Phosphorylation | score0 | HPRD | 18691976 | ||
| T82 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S83 | Phosphorylation | score0 | HPRD | 18691976, 18452278 | ||
| S86 | Phosphorylation | score0 | HPRD | 18691976, 18077418, 18669648, ... | ||
| S88 | Phosphorylation | score0 | HPRD | 18691976, 18077418, 18669648, ... | ||
| S96 | Phosphorylation | score0 | HPRD | 18691976 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S17 | L17 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S20 | Y20 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:3571 / liver cancer [ cosmic, icgc ] | |
| T82 | P82 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T288 | I288 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S338 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] | |
| Y344 | H344 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| Y344 | C344 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K455 | R455 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
DAG View