iPTMnet Report for Q8R4B8 (Nlrp3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8R4B8 / NLRP3_MOUSE
Protein Name NACHT, LRR and PYD domains-containing protein 3
Gene Name Name: Nlrp3
Synonyms:Cias1;
Organism Mus musculus (Mouse)

PRO ID PR:Q8R4B8
DAG View
PRO Name NACHT, LRR and PYD domains-containing protein 3 (mouse)
Definition A NACHT, LRR and PYD domains-containing protein 3 that is encoded in the genome of mouse.
Short Label mNLRP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8R4B8 (Nlrp3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus   UniProt 28465465
Y132 Phosphorylation PhosphoSitePlus   UniProt 34554188
Y136 Phosphorylation UniProt 34554188
Y145 Phosphorylation UniProt 34554188
S157 Phosphorylation UniProt 28465465
Y164 Phosphorylation UniProt 34554188
S194 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 28943315
S291 Phosphorylation PhosphoSitePlus   UniProt 28716882
S330 Phosphorylation PhosphoSitePlus
K380 Ubiquitination PhosphoSitePlus
K565 Ubiquitination PhosphoSitePlus
K687 Ubiquitination PhosphoSitePlus
S725 Phosphorylation PhosphoSitePlus   UniProt 28465465
S803 Phosphorylation PhosphoSitePlus   UniProt 34615873


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P35991 (Btk) Y223 Q8R4B8 (Nlrp3) unknown eFIP 26059659