iPTMnet Report for Q8NI22 (MCFD2)
Protein Information
| UniProt AC / UniProt ID | Q8NI22 / MCFD2_HUMAN |
| Protein Name | Multiple coagulation factor deficiency protein 2 precursor |
| Gene Name | Name: MCFD2 Synonyms:SDNSF; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8NI22 |
| PRO Name | multiple coagulation factor deficiency protein 2 (human) |
| Definition | A multiple coagulation factor deficiency protein 2 that is encoded in the genome of human. |
| Short Label | hMCFD2 |
| Category | organism-gene |
DAG ViewQ8NI22 (MCFD2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S32 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S34 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S38 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K62 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S94 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
| T95 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
| T98 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380, 22661428 | ||
| S113 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K130 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y135 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y138 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K143 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T95 | I95 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| Y135 | F135 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
