Protein Information

Cytoscape View

UniProt AC / UniProt ID Q8NHU3 / SMS2_HUMAN
Protein Name Phosphatidylcholine:ceramide cholinephosphotransferase 2
Gene Name Name: SGMS2
Organism Homo sapiens (Human)

DAG View
PRO Name phosphatidylcholine:ceramide cholinephosphotransferase 2 (human)
Definition A phosphatidylcholine:ceramide cholinephosphotransferase 2 that is encoded in the genome of human.
Short Label hSGMS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q8NHU3 (SGMS2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
Y24 Phosphorylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
Y56 Phosphorylation PhosphoSitePlus
Y59 Phosphorylation PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
K363 Ubiquitination PhosphoSitePlus
T365 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K116 R116 Biomuta DOID:2394 / ovarian cancer [ tcga ]
K191 M191 Biomuta DOID:1324 / lung cancer [ cosmic ]
K363 N363 Biomuta DOID:9256 / colorectal cancer [ tcga ]
K363 R363 Biomuta DOID:363 / uterine cancer [ cosmic, tcga ]
K363 Q363 Biomuta DOID:1793 / pancreatic cancer [ icgc ]