iPTMnet Report for Q8NHM5 (KDM2B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NHM5 / KDM2B_HUMAN
Protein Name Lysine-specific demethylase 2B
Gene Name Name: KDM2B
Synonyms:CXXC2,FBL10,FBXL10,JHDM1B,NDY1;
Organism Homo sapiens (Human)

PRO ID PR:Q8NHM5
DAG View
PRO Name lysine-specific demethylase 2B (human)
Definition A lysine-specific demethylase 2B that is encoded in the genome of human.
Short Label hKDM2B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NHM5 (KDM2B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y50 Phosphorylation PhosphoSitePlus
S57 Phosphorylation PhosphoSitePlus   UniProt 23186163
K73 Ubiquitination PhosphoSitePlus
Y94 Phosphorylation PhosphoSitePlus
K111 Ubiquitination PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
T124 Phosphorylation PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus
T145 Phosphorylation PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
T149 Phosphorylation PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
Y223 Phosphorylation PhosphoSitePlus
Y229 Phosphorylation PhosphoSitePlus
T440 Phosphorylation PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus
T444 Phosphorylation PhosphoSitePlus
S445 Phosphorylation PhosphoSitePlus
T447 Phosphorylation PhosphoSitePlus
T449 Phosphorylation PhosphoSitePlus
T472 Phosphorylation PhosphoSitePlus
S474 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 21406692, 23186163
S477 Phosphorylation PhosphoSitePlus   UniProt 21406692
S480 Phosphorylation PhosphoSitePlus
T493 Phosphorylation PhosphoSitePlus   UniProt 21406692, 19690332
T495 Phosphorylation PhosphoSitePlus
S497 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 15302935
T500 Phosphorylation PhosphoSitePlus
S503 Phosphorylation PhosphoSitePlus
K515 Ubiquitination PhosphoSitePlus
K532 Ubiquitination PhosphoSitePlus
S593 Phosphorylation PhosphoSitePlus
Y739 Phosphorylation PhosphoSitePlus
S741 Phosphorylation PhosphoSitePlus
S746 Phosphorylation PhosphoSitePlus
K758 Acetylation PhosphoSitePlus
K765 Acetylation PhosphoSitePlus
S768 Phosphorylation PhosphoSitePlus
S795 Phosphorylation PhosphoSitePlus
S813 Phosphorylation PhosphoSitePlus
S820 Phosphorylation PhosphoSitePlus
T823 Phosphorylation phospho.ELM 18669648
S824 Phosphorylation PhosphoSitePlus
S827 Phosphorylation PhosphoSitePlus
S832 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S840 Phosphorylation PhosphoSitePlus
S842 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T850 Phosphorylation PhosphoSitePlus
K884 Ubiquitination PhosphoSitePlus
K890 Methylation PhosphoSitePlus
K890 Sumoylation PhosphoSitePlus
S912 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S913 Phosphorylation PhosphoSitePlus
S914 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T916 Phosphorylation PhosphoSitePlus
S947 Phosphorylation PhosphoSitePlus
S951 Phosphorylation PhosphoSitePlus   UniProt 23186163
S975 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
S979 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
T1004 Phosphorylation PhosphoSitePlus
S1015 Phosphorylation PhosphoSitePlus
S1018 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1029 Phosphorylation PhosphoSitePlus
S1031 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K1111 Ubiquitination PhosphoSitePlus
C1172 Methylation IEDB 31844290
K1187 Ubiquitination PhosphoSitePlus
R1231 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S57 Phosphorylation HPRD 19664994
Y223 Phosphorylation HPRD 20068231, 17924679
S443 Phosphorylation HPRD 19664995
T444 Phosphorylation HPRD 18452278
S445 Phosphorylation HPRD 20068231, 18452278
S474 Phosphorylation HPRD 15302935
S497 Phosphorylation HPRD 15302935, 19664995
T823 Phosphorylation HPRD 18669648
S832 Phosphorylation HPRD 18669648
S842 Phosphorylation HPRD 18669648
S912 Phosphorylation HPRD 18669648, 19664995
S913 Phosphorylation HPRD 19413330, 19664995
S914 Phosphorylation HPRD 19413330, 18669648, 19664994, ...19664995
T916 Phosphorylation HPRD 19664995
S975 Phosphorylation HPRD 18452278
S979 Phosphorylation HPRD 18452278
S1029 Phosphorylation HPRD 20068231
S1031 Phosphorylation HPRD 19651622, 18669648, 18452278
Site PTM Type PTM Enzyme Score Source PMID
S26 Phosphorylation HPRD 19664994
Y192 Phosphorylation HPRD 20068231, 17924679
S412 Phosphorylation HPRD 19664995
T413 Phosphorylation HPRD 18452278
S414 Phosphorylation HPRD 20068231, 18452278
S443 Phosphorylation HPRD 15302935
S466 Phosphorylation HPRD 15302935, 19664995
S843 Phosphorylation HPRD 18669648, 19664995
S844 Phosphorylation HPRD 19413330, 19664995
S845 Phosphorylation HPRD 19413330, 18669648, 19664994, ...19664995
T847 Phosphorylation HPRD 19664995
S906 Phosphorylation HPRD 18452278
S910 Phosphorylation HPRD 18452278
S960 Phosphorylation HPRD 20068231
S962 Phosphorylation HPRD 19651622, 18669648, 18452278


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P01100 (FOS) S374 Q8NHM5 (KDM2B) decreased_association eFIP 26725323