iPTMnet Report for Q8NG68 (TTL)
Protein Information
| UniProt AC / UniProt ID | Q8NG68 / TTL_HUMAN |
| Protein Name | Tubulin--tyrosine ligase |
| Gene Name | Name: TTL |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8NG68 |
| PRO Name | tubulin--tyrosine ligase (human) |
| Definition | A tubulin--tyrosine ligase that is encoded in the genome of human. |
| Short Label | hTTL |
| Category | organism-gene |
DAG ViewQ8NG68 (TTL) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T24 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K138 | Acetylation | score1 | PhosphoSitePlus | |||
| K150 | Acetylation | score1 | PhosphoSitePlus | |||
| K150 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S152 | Phosphorylation | score0 | RLIMS-P | 23358242 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K138 | N138 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S152 | L152 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
