iPTMnet Report for Q8NFZ5 (TNIP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NFZ5 / TNIP2_HUMAN
Protein Name TNFAIP3-interacting protein 2
Gene Name Name: TNIP2
Synonyms:ABIN2,FLIP1;
Organism Homo sapiens (Human)

PRO ID PR:Q8NFZ5
DAG View
PRO Name TNFAIP3-interacting protein 2 (human)
Definition A TNFAIP3-interacting protein 2 that is encoded in the genome of human.
Short Label hTNIP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NFZ5 (TNIP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
S7 Phosphorylation PhosphoSitePlus   UniProt 24275569
T22 Phosphorylation PhosphoSitePlus
Y24 Phosphorylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
S146 Phosphorylation PhosphoSitePlus
C165 Methylation IEDB 31844290
K170 Ubiquitination PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
K205 Ubiquitination PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
K330 Ubiquitination PhosphoSitePlus
S333 Phosphorylation IEDB 32357974
S339 O-Glycosylation GlyGen 35254053
S339 Phosphorylation PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S186 Phosphorylation HPRD 18691976


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S146 F146 Biomuta DOID:1319 / brain cancer [ cosmic ]
S186 N186 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K330 E330 Biomuta DOID:4606 / bile duct cancer [ cosmic ]