iPTMnet Report for Q8NFY9 (KBTBD8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NFY9 / KBTB8_HUMAN
Protein Name Kelch repeat and BTB domain-containing protein 8
Gene Name Name: KBTBD8
Synonyms:KIAA1842,TAKRP;
Organism Homo sapiens (Human)

PRO ID PR:Q8NFY9
DAG View
PRO Name kelch repeat and BTB domain-containing protein 8 (human)
Definition A kelch repeat and BTB domain-containing protein 8 that is encoded in the genome of human.
Short Label hKBTBD8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NFY9 (KBTBD8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K37 Ubiquitination PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
K178 Acetylation PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K268 Ubiquitination PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
K373 Ubiquitination PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
K409 Ubiquitination PhosphoSitePlus
T498 Phosphorylation PhosphoSitePlus
Y502 Phosphorylation PhosphoSitePlus
K513 Ubiquitination PhosphoSitePlus
Y524 Phosphorylation PhosphoSitePlus
C596 Methylation IEDB 31844290


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K238 R238 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K373 I373 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
Y502 H502 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]