iPTMnet Report for Q8NFY4 (SEMA6D)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NFY4 / SEM6D_HUMAN
Protein Name Semaphorin-6D precursor
Gene Name Name: SEMA6D
Synonyms:KIAA1479;
Organism Homo sapiens (Human)

PRO ID PR:Q8NFY4
DAG View
PRO Name semaphorin-6D (human)
Definition A semaphorin-6D that is encoded in the genome of human.
Short Label hSEMA6D
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NFY4 (SEMA6D) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S201 Phosphorylation PhosphoSitePlus
K260 Acetylation PhosphoSitePlus
K272 Acetylation PhosphoSitePlus
Y472 Phosphorylation PhosphoSitePlus
T613 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
K699 Ubiquitination PhosphoSitePlus
S703 Phosphorylation PhosphoSitePlus
S723 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y728 Phosphorylation PhosphoSitePlus
S734 Phosphorylation PhosphoSitePlus
Y738 Phosphorylation PhosphoSitePlus
S744 Phosphorylation PhosphoSitePlus   UniProt 23186163
T754 Phosphorylation PhosphoSitePlus
S756 Phosphorylation PhosphoSitePlus
T773 Phosphorylation PhosphoSitePlus   UniProt 23186163
S776 Phosphorylation PhosphoSitePlus
S792 Phosphorylation PhosphoSitePlus
Y837 Phosphorylation PhosphoSitePlus
S863 Phosphorylation PhosphoSitePlus
S865 Phosphorylation PhosphoSitePlus
S928 Phosphorylation PhosphoSitePlus
Y930 Phosphorylation PhosphoSitePlus
S931 Phosphorylation PhosphoSitePlus   UniProt 23186163
S957 Phosphorylation PhosphoSitePlus   UniProt 23186163
S973 Phosphorylation PhosphoSitePlus
S975 Phosphorylation PhosphoSitePlus
S983 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y1000 Phosphorylation PhosphoSitePlus
Y1011 Phosphorylation PhosphoSitePlus
T1015 Phosphorylation PhosphoSitePlus
S1026 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
S1030 Phosphorylation PhosphoSitePlus
Y1031 Phosphorylation PhosphoSitePlus
T1062 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S703 F703 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S734 F734 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S734 Y734 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
T773 I773 Biomuta DOID:4159 / skin cancer [ cosmic ]
S792 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S863 P863 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S928 L928 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S957 Y957 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S973 P973 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S975 Y975 Biomuta DOID:363 / uterine cancer [ icgc ]
T1015 K1015 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1026 P1026 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1026 Y1026 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1030 R1030 Biomuta DOID:3571 / liver cancer [ cosmic ]
T1062 A1062 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]