iPTMnet Report for Q8NFW8 (CMAS)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NFW8 / NEUA_HUMAN
Protein Name N-acylneuraminate cytidylyltransferase
Gene Name Name: CMAS
Organism Homo sapiens (Human)

PRO ID PR:Q8NFW8
DAG View
PRO Name N-acylneuraminate cytidylyltransferase (human)
Definition An N-acylneuraminate cytidylyltransferase that is encoded in the genome of human.
Short Label hCMAS
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NFW8 (CMAS) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
K6 Acetylation PhosphoSitePlus
K6 Ubiquitination PhosphoSitePlus
R16 Methylation PhosphoSitePlus
R18 Methylation PhosphoSitePlus
R21 Methylation PhosphoSitePlus
K26 Acetylation PhosphoSitePlus
R37 Methylation PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
T92 Phosphorylation PhosphoSitePlus
C148 Methylation IEDB 31844290
Y166 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
Y292 Phosphorylation PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
K342 Acetylation PhosphoSitePlus
K382 Ubiquitination PhosphoSitePlus
K399 Methylation PhosphoSitePlus
K399 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K6 N6 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
R18 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K61 N61 Biomuta DOID:3571 / liver cancer [ cosmic ]
K64 R64 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
C148 Y148 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S168 C168 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K342 E342 Biomuta DOID:1324 / lung cancer [ cosmic ]