Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NFW1 / COMA1_HUMAN
Protein Name Collagen alpha-1(XXII) chain precursor
Gene Name Name: COL22A1
Organism Homo sapiens (Human)

PRO ID PR:Q8NFW1
DAG View
PRO Name collagen alpha-1(XXII) chain (human)
Definition A collagen alpha-1(XXII) chain that is encoded in the genome of human.
Short Label hCOL22A1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NFW1 (COL22A1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S34 Phosphorylation PhosphoSitePlus
Y37 Phosphorylation PhosphoSitePlus
T45 Phosphorylation PhosphoSitePlus
Y110 Phosphorylation PhosphoSitePlus
T117 Phosphorylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus
T449 O-Glycosylation GlyGen 30459171
T462 O-Glycosylation GlyGen 30459171
S534 Phosphorylation PhosphoSitePlus
K870 Acetylation PhosphoSitePlus
S930 Phosphorylation PhosphoSitePlus
K983 Acetylation PhosphoSitePlus
S1035 Phosphorylation PhosphoSitePlus
S1038 Phosphorylation PhosphoSitePlus
R1039 Methylation PhosphoSitePlus
T1281 Phosphorylation PhosphoSitePlus
S1284 Phosphorylation PhosphoSitePlus
S1293 Phosphorylation PhosphoSitePlus
K1379 Acetylation PhosphoSitePlus
K1385 Acetylation PhosphoSitePlus
K1401 Acetylation PhosphoSitePlus
K1404 Acetylation PhosphoSitePlus
K1410 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S34 I34 Biomuta DOID:1324 / lung cancer [ tcga ]
T117 M117 Biomuta DOID:1793 / pancreatic cancer [ icgc, tcga ] DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ tcga ]
S534 F534 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S930 N930 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S930 I930 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1038 R1038 Biomuta DOID:3571 / liver cancer [ icgc ]
T1281 I1281 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S1284 A1284 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]
S1293 Y1293 Biomuta DOID:2394 / ovarian cancer [ tcga ]
K1379 N1379 Biomuta DOID:3070 / malignant glioma [ tcga ]