iPTMnet Report for Q8NFU5 (IPMK)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NFU5 / IPMK_HUMAN
Protein Name Inositol polyphosphate multikinase
Gene Name Name: IPMK
Synonyms:IMPK;
Organism Homo sapiens (Human)

PRO ID PR:Q8NFU5
DAG View
PRO Name inositol polyphosphate multikinase (human)
Definition An inositol polyphosphate multikinase that is encoded in the genome of human.
Short Label hIPMK
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NFU5 (IPMK) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19369195
T3 Phosphorylation PhosphoSitePlus
S7 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 19369195
T21 Phosphorylation HPRD   PhosphoSitePlus 18691976
S22 Phosphorylation HPRD   PhosphoSitePlus 18691976
S27 Phosphorylation HPRD   PhosphoSitePlus 18691976
T28 Phosphorylation HPRD   PhosphoSitePlus 18691976
Y113 Phosphorylation PhosphoSitePlus
Y114 Phosphorylation PhosphoSitePlus
S118 Phosphorylation PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
K208 Acetylation PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
S229 Phosphorylation PhosphoSitePlus
K232 Ubiquitination PhosphoSitePlus
T266 Phosphorylation PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
S315 O-Glycosylation GlyGen 30379171
Y318 Phosphorylation PhosphoSitePlus
Y325 Phosphorylation PhosphoSitePlus
T333 Phosphorylation PhosphoSitePlus
S334 Phosphorylation PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus
S412 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 T2 Biomuta DOID:363 / uterine cancer [ icgc ]
T28 I28 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y113 C113 Biomuta DOID:363 / uterine cancer [ icgc ]
Y114 F114 Biomuta DOID:1612 / breast cancer [ cosmic ]
S118 P118 Biomuta DOID:363 / uterine cancer [ icgc ]
K208 N208 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S315 P315 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S334 L334 Biomuta DOID:4159 / skin cancer [ cosmic ]