iPTMnet Report for Q8NFQ8 (TOR1AIP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NFQ8 / TOIP2_HUMAN
Protein Name Torsin-1A-interacting protein 2
Gene Name Name: TOR1AIP2
Synonyms:IFRG15,LULL1;
Organism Homo sapiens (Human)

Interactive Sequence View

Select/align proteoforms across species


Q8NFQ8 (TOR1AIP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 21406692
S4 O-Glycosylation GlyGen 33465208, 35254053
S4 Phosphorylation PhosphoSitePlus
R7 Methylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus   UniProt 21406692
T58 Phosphorylation PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus
T86 Phosphorylation PhosphoSitePlus
S93 Phosphorylation PhosphoSitePlus   UniProt 23186163
S118 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S120 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S150 Phosphorylation PhosphoSitePlus
T155 Phosphorylation PhosphoSitePlus
S158 Phosphorylation PhosphoSitePlus
S163 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S167 Phosphorylation phospho.ELM 18669648
S168 Phosphorylation PhosphoSitePlus
T176 Phosphorylation PhosphoSitePlus   UniProt 24275569
S188 Phosphorylation PhosphoSitePlus
T193 Phosphorylation PhosphoSitePlus   UniProt 23186163
K195 Ubiquitination PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
N286 N-Glycosylation GlyGen 23090970, 29741879, 24190977
S288 O-Glycosylation GlyGen 33465208, 35254053
N289 N-Glycosylation GlyGen 24190977
K309 Ubiquitination PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
S326 Phosphorylation PhosphoSitePlus
K425 Ubiquitination PhosphoSitePlus
N428 N-Glycosylation GlyGen 24190977
T433 Phosphorylation PhosphoSitePlus
S440 Phosphorylation PhosphoSitePlus
K442 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S118 Phosphorylation HPRD 19651622, 18669648, 20068231
S120 Phosphorylation HPRD 19651622, 18669648, 20068231
S122 Phosphorylation HPRD 19651622, 20068231
S150 Phosphorylation HPRD 18077418
S158 Phosphorylation HPRD 18691976, 18077418
S163 Phosphorylation HPRD 18669648
S167 Phosphorylation HPRD 18669648
S326 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S70 L70 Biomuta DOID:4159 / skin cancer [ cosmic ]
K195 T195 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K195 * Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S288 F288 Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
K425 M425 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]