Protein Information

Cytoscape View

UniProt AC / UniProt ID Q8NFP7 / NUD10_HUMAN
Protein Name Diphosphoinositol polyphosphate phosphohydrolase 3-alpha
Gene Name Name: NUDT10
Organism Homo sapiens (Human)

DAG View
PRO Name diphosphoinositol polyphosphate phosphohydrolase 3-alpha (human)
Definition A diphosphoinositol polyphosphate phosphohydrolase 3-alpha that is encoded in the genome of human.
Short Label hNUDT10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q8NFP7 (NUDT10) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
Y11 Phosphorylation PhosphoSitePlus
Y67 Phosphorylation PhosphoSitePlus
K73 Methylation PhosphoSitePlus
K75 Methylation PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
S148 Phosphorylation HPRD   PhosphoSitePlus 19413330
T150 Phosphorylation HPRD   PhosphoSitePlus 19413330
S154 Phosphorylation HPRD   PhosphoSitePlus 19413330
S158 Phosphorylation HPRD   PhosphoSitePlus 19413330
S159 Phosphorylation HPRD   PhosphoSitePlus 19413330
S162 Phosphorylation HPRD   PhosphoSitePlus 19413330

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y11 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K73 T73 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S159 L159 Biomuta DOID:1115 / sarcoma [ tcga ]
S162 I162 Biomuta DOID:3571 / liver cancer [ icgc ]