iPTMnet Report for Q8NFM4 (ADCY4)
Protein Information
| UniProt AC / UniProt ID | Q8NFM4 / ADCY4_HUMAN |
| Protein Name | Adenylate cyclase type 4 |
| Gene Name | Name: ADCY4 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8NFM4 |
| PRO Name | adenylate cyclase type 4 (human) |
| Definition | An adenylate cyclase type 4 that is encoded in the genome of human. |
| Short Label | hADCY4 |
| Category | organism-gene |
DAG ViewQ8NFM4 (ADCY4) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S6 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S253 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K267 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y444 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T459 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K489 | Acetylation | score1 | PhosphoSitePlus | |||
| S499 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S919 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K923 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K1001 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K267 | M267 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| K267 | N267 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
| K489 | N489 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S499 | I499 | Biomuta | DOID:1612 / breast cancer [ cosmic ] |
