Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NFH8 / REPS2_HUMAN
Protein Name RalBP1-associated Eps domain-containing protein 2
Gene Name Name: REPS2
Synonyms:POB1;
Organism Homo sapiens (Human)

PRO ID PR:Q8NFH8
DAG View
PRO Name RalBP1-associated Eps domain-containing protein 2 (human)
Definition A RalBP1-associated Eps domain-containing protein 2 that is encoded in the genome of human.
Short Label hREPS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NFH8 (REPS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y103 Phosphorylation PhosphoSitePlus
T107 Phosphorylation PhosphoSitePlus
Y110 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
S195 Phosphorylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
S199 Phosphorylation PhosphoSitePlus
Y212 Phosphorylation PhosphoSitePlus
S213 Phosphorylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
S218 Phosphorylation PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus   UniProt 24275569
S260 Phosphorylation PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus
T446 Phosphorylation PhosphoSitePlus
S459 Phosphorylation PhosphoSitePlus
S461 Phosphorylation PhosphoSitePlus
Y462 Phosphorylation PhosphoSitePlus
S463 Phosphorylation P06493 (CDK1) PhosphoSitePlus 10764745
S464 Phosphorylation PhosphoSitePlus
S466 Phosphorylation PhosphoSitePlus
T479 Phosphorylation PhosphoSitePlus   UniProt 24275569
S489 Phosphorylation PhosphoSitePlus
S492 Phosphorylation PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus   UniProt 24275569
S503 Phosphorylation PhosphoSitePlus
S509 Phosphorylation PhosphoSitePlus
S544 Phosphorylation PhosphoSitePlus
Y558 Phosphorylation PhosphoSitePlus
S563 Phosphorylation PhosphoSitePlus
K610 Acetylation PhosphoSitePlus
S631 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S121 Phosphorylation HPRD 19413330
S254 Phosphorylation HPRD 20166139
Y558 Phosphorylation HPRD 19901323
Site PTM Type PTM Enzyme Score Source PMID
S411 Phosphorylation P06493 (CDK1) neXtProt 10764745
Site PTM Type PTM Enzyme Score Source PMID
S55 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S121 Phosphorylation HPRD 19413330
S253 Phosphorylation HPRD 20166139
Y557 Phosphorylation HPRD 19901323


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S254 F254 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
S260 P260 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S304 Y304 Biomuta DOID:363 / uterine cancer [ tcga ]
S459 C459 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
S461 A461 Biomuta DOID:4362 / cervical cancer [ icgc, tcga ]
S463 F463 Biomuta DOID:3070 / malignant glioma [ cosmic ]
S493 F493 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S503 N503 Biomuta DOID:1909 / melanoma [ cosmic ]