iPTMnet Report for Q8NFH5 (NUP35)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NFH5 / NUP35_HUMAN
Protein Name Nucleoporin NUP35
Gene Name Name: NUP35
Synonyms:MP44,NUP53;
Organism Homo sapiens (Human)

PRO ID PR:Q8NFH5
DAG View
PRO Name nucleoporin NUP35 (human)
Definition A nucleoporin NUP35 that is encoded in the genome of human.
Short Label hNUP35
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NFH5 (NUP35) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
T48 Phosphorylation PhosphoSitePlus
S53 O-Glycosylation GlyGen 23301498, 33214551, 28510447, ...32938750, 30059200, 30620550, 34019948, 31492838, 29485866, 35289036, 35254053, 22121020, 28657654, 29237092
S53 Phosphorylation PhosphoSitePlus   UniProt 23186163
S55 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S58 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S66 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S73 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 20068231
K83 Ubiquitination PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
S93 O-Glycosylation GlyGen 23301498, 33214551, 28510447, ...30059200, 30620550, 34019948, 31492838, 29485866, 35289036, 35254053, 22121020, 28657654, 29237092
S93 Phosphorylation PhosphoSitePlus
Y95 Phosphorylation PhosphoSitePlus
S99 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S100 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336, 18669648, ...19690332, 20068231
S105 Phosphorylation PhosphoSitePlus
T106 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...18220336
T109 Phosphorylation PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus
S121 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
T127 Phosphorylation PhosphoSitePlus
S128 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T129 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T132 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S135 Phosphorylation PhosphoSitePlus
S138 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K227 Ubiquitination PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
S258 Phosphorylation PhosphoSitePlus
S259 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S261 Phosphorylation PhosphoSitePlus
T265 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K269 Ubiquitination PhosphoSitePlus
T270 Phosphorylation PhosphoSitePlus
T273 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 18669648, ...24275569, 20068231
T275 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S279 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 16964243, ...20068231
T280 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16964243, 20068231
S284 Phosphorylation PhosphoSitePlus   UniProt 23186163
T285 Phosphorylation PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
S296 O-Glycosylation GlyGen 23301498, 33214551, 28510447, ...30059200, 30620550, 34019948, 31492838, 29485866, 35289036, 35254053, 22121020, 28657654, 29237092
T297 O-Glycosylation GlyGen 23301498, 33214551, 28510447, ...30059200, 30620550, 34019948, 31492838, 29485866, 35289036, 35254053, 22121020, 28657654, 29237092
S298 O-Glycosylation GlyGen 23301498, 33214551, 28510447, ...32938750, 30059200, 30620550, 34019948, 31492838, 29485866, 35289036, 35254053, 22121020, 28657654, 29237092
S298 Phosphorylation PhosphoSitePlus
Y300 Phosphorylation PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus
T308 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K311 Ubiquitination PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S15 Phosphorylation HPRD 20068231
S22 Phosphorylation HPRD 20068231
T24 Phosphorylation HPRD 20068231
S25 Phosphorylation HPRD 20068231
T48 Phosphorylation HPRD 20068231
S55 Phosphorylation HPRD 18669648, 20068231
S58 Phosphorylation HPRD 18669648, 20068231
S66 Phosphorylation HPRD 19651622, 18669648, 20068231
S73 Phosphorylation HPRD 17081983, 18767875, 19664995, ...19691289, 19651622, 18669648, 20068231
S93 Phosphorylation HPRD 20068231
S99 Phosphorylation HPRD 18669648, 20068231
S100 Phosphorylation HPRD 19413330, 18669648, 20068231
S105 Phosphorylation HPRD 19664995, 20068231
T106 Phosphorylation HPRD 19413330, 18669648, 19664995, ...20068231
T109 Phosphorylation HPRD 20068231
S121 Phosphorylation HPRD 18669648, 20068231
S128 Phosphorylation HPRD 18669648
T129 Phosphorylation HPRD 18669648, 20068231
T132 Phosphorylation HPRD 18669648
S138 Phosphorylation HPRD 18669648, 20068231
S259 Phosphorylation HPRD 17322306, 18669648, 19007248, ...20068231, 19664995
T265 Phosphorylation HPRD 17322306, 18669648, 19664995, ...20068231
T273 Phosphorylation HPRD 19413330, 16964243, 19664995, ...19691289, 19651622, 18669648, 20068231
T275 Phosphorylation HPRD 19651622, 18669648, 19664995
S279 Phosphorylation HPRD 19651622, 18669648, 16964243, ...20068231
T280 Phosphorylation HPRD 19651622, 18669648, 16964243, ...20068231, 19664995
T308 Phosphorylation HPRD 18669648, 20068231
S314 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S22 P22 Biomuta DOID:4159 / skin cancer [ cosmic ]
S25 F25 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T106 K106 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T127 A127 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S128 P128 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S258 L258 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S304 P304 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T308 M308 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S314 R314 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]