iPTMnet Report Q8NFH3 NUP43

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q8NFH3 / NUP43_HUMAN
Protein Name	Nucleoporin Nup43
Gene Name	Name: NUP43
Organism	Homo sapiens (Human)

PRO ID	PR:Q8NFH3 DAG View
PRO Name	nucleoporin Nup43 (human)
Definition	A nucleoporin Nup43 that is encoded in the genome of human.
Short Label	hNUP43
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q8NFH3 (NUP43) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	M1	Acetylation		score1	UniProt	22814378
	K7	Ubiquitination		score1	PhosphoSitePlus
	K12	Ubiquitination		score1	PhosphoSitePlus
	S57	Phosphorylation		score2	phospho.ELM PhosphoSitePlus	22067460
	K196	Ubiquitination		score1	PhosphoSitePlus
	T251	Phosphorylation		score1	PhosphoSitePlus
	S255	Phosphorylation		score1	PhosphoSitePlus
	S299	Phosphorylation		score1	PhosphoSitePlus
	S317	Phosphorylation		score1	PhosphoSitePlus
	S348	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T251	Phosphorylation		score0	HPRD	20068231
	S255	Phosphorylation		score0	HPRD	20068231
	S299	Phosphorylation		score0	HPRD	19691289
	S317	Phosphorylation		score0	HPRD	19007248

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
M1	I1	Biomuta		DOID:11054 / urinary bladder cancer [ icgc ]
T251	S251	Biomuta		DOID:3571 / liver cancer [ cosmic ]
S255	C255	Biomuta		DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S317	I317	Biomuta		DOID:1319 / brain cancer [ cosmic, icgc ]