iPTMnet Report for Q8NFA0 (USP32)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NFA0 / UBP32_HUMAN
Protein Name Ubiquitin carboxyl-terminal hydrolase 32 precursor
Gene Name Name: USP32
Synonyms:USP10;
Organism Homo sapiens (Human)

PRO ID PR:Q8NFA0
DAG View
PRO Name ubiquitin carboxyl-terminal hydrolase 32 (human)
Definition A ubiquitin carboxyl-terminal hydrolase 32 that is encoded in the genome of human.
Short Label hUSP32
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NFA0 (USP32) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C46 Methylation IEDB 31844290
S101 Phosphorylation PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus
Y110 Phosphorylation PhosphoSitePlus
K145 Acetylation PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
S165 Phosphorylation IEDB 35494241
K274 Methylation PhosphoSitePlus
Y410 Phosphorylation PhosphoSitePlus
S452 Phosphorylation PhosphoSitePlus
Y453 Phosphorylation PhosphoSitePlus
C490 Methylation IEDB 31844290
S539 Phosphorylation phospho.ELM 15302935
K589 Ubiquitination PhosphoSitePlus
S627 Phosphorylation PhosphoSitePlus
Y676 Phosphorylation PhosphoSitePlus
K806 Ubiquitination PhosphoSitePlus
K847 Ubiquitination PhosphoSitePlus
K951 Ubiquitination PhosphoSitePlus
S1127 Phosphorylation PhosphoSitePlus
K1162 Ubiquitination PhosphoSitePlus
Y1173 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T1243 Phosphorylation PhosphoSitePlus
K1323 Ubiquitination PhosphoSitePlus
T1326 Phosphorylation PhosphoSitePlus
S1349 Phosphorylation PhosphoSitePlus
S1350 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1359 Phosphorylation PhosphoSitePlus
S1361 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S1363 Phosphorylation PhosphoSitePlus
S1364 Phosphorylation PhosphoSitePlus
S1366 Phosphorylation PhosphoSitePlus
S1371 Phosphorylation PhosphoSitePlus
S1372 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...19690332
S1376 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1393 Phosphorylation PhosphoSitePlus
S1394 Phosphorylation PhosphoSitePlus
S1398 Phosphorylation PhosphoSitePlus
T1401 Phosphorylation PhosphoSitePlus
S1416 Phosphorylation PhosphoSitePlus
S1422 Phosphorylation PhosphoSitePlus
S1423 Phosphorylation PhosphoSitePlus
S1430 Phosphorylation PhosphoSitePlus
S1454 Phosphorylation PhosphoSitePlus   UniProt 24275569
K1537 Ubiquitination PhosphoSitePlus
Y1539 Phosphorylation PhosphoSitePlus
Y1541 Phosphorylation PhosphoSitePlus
S1544 Phosphorylation PhosphoSitePlus
S1545 Phosphorylation PhosphoSitePlus
S1587 Phosphorylation PhosphoSitePlus
S1588 Phosphorylation PhosphoSitePlus   UniProt 23186163
Site PTM Type PTM Enzyme Score Source PMID
Y1173 Phosphorylation HPRD 18669648
S1361 Phosphorylation HPRD 19651622, 17081983
S1366 Phosphorylation HPRD 19651622
S1372 Phosphorylation HPRD 19651622, 17081983
S1423 Phosphorylation HPRD 19664995


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S107 F107 Biomuta DOID:1612 / breast cancer [ cosmic ]
Y110 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K274 M274 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y410 C410 Biomuta [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S539 L539 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K847 M847 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1127 F1127 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1350 L1350 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ icgc ] DOID:4362 / cervical cancer [ cosmic ] DOID:9256 / colorectal cancer [ icgc ] DOID:1612 / breast cancer [ cosmic, icgc ]
S1361 R1361 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S1361 N1361 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1366 I1366 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S1376 Y1376 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:363 / uterine cancer [ cosmic, icgc ]
S1544 N1544 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1545 R1545 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]