iPTMnet Report for Q8NEZ5 (FBXO22)
Protein Information
| UniProt AC / UniProt ID | Q8NEZ5 / FBX22_HUMAN |
| Protein Name | F-box only protein 22 |
| Gene Name | Name: FBXO22 Synonyms:FBX22; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8NEZ5 |
| PRO Name | F-box only protein 22 (human) |
| Definition | An F-box only protein 22 that is encoded in the genome of human. |
| Short Label | hFBXO22 |
| Category | organism-gene |
DAG ViewQ8NEZ5 (FBXO22) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 19413330, 22814378, 22223895 | ||
| K40 | Acetylation | score1 | PhosphoSitePlus | |||
| K40 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C83 | Methylation | score1 | IEDB | 31844290 | ||
| Y104 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S128 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K137 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S160 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S162 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K194 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K194 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K300 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K337 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C83 | Y83 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:363 / uterine cancer [ icgc ] | |
| Y104 | C104 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
