iPTMnet Report for Q8NEZ4 (KMT2C)
Protein Information
UniProt AC / UniProt ID | Q8NEZ4 / KMT2C_HUMAN |
Protein Name | Histone-lysine N-methyltransferase 2C |
Gene Name | Name: KMT2C Synonyms:HALR,KIAA1506,MLL3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8NEZ4 |
PRO Name | histone-lysine N-methyltransferase 2C (human) |
Definition | A histone-lysine N-methyltransferase 2C that is encoded in the genome of human. |
Short Label | hKMT2C |
Category | organism-gene |
Q8NEZ4 (KMT2C) as Substrate
Site | PTM Type | PTM Enzyme |
Score
| Source | PMID | |
---|---|---|---|---|---|---|
S28 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S46 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
S68 | Phosphorylation | score1 | PhosphoSitePlus | |||
S89 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
S111 | Phosphorylation | score1 | PhosphoSitePlus | |||
S113 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S116 | Phosphorylation | score1 | PhosphoSitePlus | |||
S119 | Phosphorylation | score1 | PhosphoSitePlus | |||
S143 | Phosphorylation | score1 | PhosphoSitePlus | |||
S177 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y181 | Phosphorylation | score1 | PhosphoSitePlus | |||
S200 | Phosphorylation | score2 | IEDB PhosphoSitePlus UniProt | 27920218, 24275569 | ||
S207 | Phosphorylation | score1 | PhosphoSitePlus | |||
S210 | Phosphorylation | score1 | PhosphoSitePlus | |||
S217 | Phosphorylation | score1 | PhosphoSitePlus | |||
S620 | Phosphorylation | score1 | PhosphoSitePlus | |||
S625 | Phosphorylation | score1 | PhosphoSitePlus | |||
S631 | Phosphorylation | score1 | PhosphoSitePlus | |||
S701 | Phosphorylation | score1 | PhosphoSitePlus | |||
S753 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y754 | Phosphorylation | score1 | PhosphoSitePlus | |||
K758 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K827 | Acetylation | score1 | PhosphoSitePlus | |||
S836 | Phosphorylation | score1 | PhosphoSitePlus | |||
K843 | Methylation | score1 | PhosphoSitePlus | |||
S854 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K870 | Ubiquitination | score1 | PhosphoSitePlus | |||
R886 | Methylation | score1 | PhosphoSitePlus | |||
K893 | Acetylation | score1 | PhosphoSitePlus | |||
S948 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1043 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1219 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1225 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1228 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1248 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1250 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1251 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1278 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1301 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
S1307 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1310 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1375 | O-Glycosylation | score1 | GlyGen | 23301498, 30379171, 32574038, ...34019948, 30059200, 35132862, 31492838, 35254053 | ||
S1379 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1380 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1387 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1395 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1435 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1493 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1508 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
S1602 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1724 | O-Glycosylation | score1 | GlyGen | 23301498, 30379171, 32574038, ...34019948, 30059200, 35132862, 31492838, 35254053 | ||
S1728 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
S1729 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
S1733 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1766 | Acetylation | score1 | PhosphoSitePlus | |||
K1772 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
T1837 | O-Glycosylation | score1 | GlyGen | 32938750 | ||
S1840 | O-Glycosylation | score1 | GlyGen | 23301498, 30379171, 32574038, ...32938750, 34019948, 30059200, 35132862, 31492838, 35254053 | ||
S1843 | O-Glycosylation | score1 | GlyGen | 23301498, 30379171, 32574038, ...34019948, 30059200, 35132862, 31492838, 35254053 | ||
S1878 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1904 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1919 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1947 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1981 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1985 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1987 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K1996 | Ubiquitination | score1 | PhosphoSitePlus | |||
K2009 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
S2011 | O-Glycosylation | score1 | GlyGen | 23301498, 30379171, 32574038, ...34019948, 30059200, 35132862, 31492838, 35254053 | ||
S2011 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2068 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2117 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2132 | Phosphorylation | score1 | PhosphoSitePlus | |||
T2137 | Phosphorylation | score1 | PhosphoSitePlus | |||
R2211 | Methylation | score1 | PhosphoSitePlus | |||
S2215 | O-Glycosylation | score1 | GlyGen | 23301498, 30379171, 32574038, ...34019948, 30059200, 35132862, 31492838, 35254053 | ||
T2224 | Phosphorylation | score1 | PhosphoSitePlus | |||
R2226 | Methylation | score1 | PhosphoSitePlus | |||
R2228 | Methylation | score1 | PhosphoSitePlus | |||
S2230 | O-Glycosylation | score1 | GlyGen | 23301498, 30379171, 32574038, ...35254053, 34019948, 30059200, 35132862, 31492838, 30620550 | ||
T2234 | O-Glycosylation | score1 | GlyGen | 32574038 | ||
R2235 | Methylation | score1 | PhosphoSitePlus | |||
T2239 | Phosphorylation | score1 | PhosphoSitePlus | |||
R2267 | Methylation | score1 | PhosphoSitePlus | |||
R2277 | Methylation | score2 | IEDB PhosphoSitePlus | 27503676 | ||
R2289 | Methylation | score1 | PhosphoSitePlus | |||
S2291 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2302 | Phosphorylation | score1 | PhosphoSitePlus | |||
T2305 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2308 | O-Glycosylation | score1 | GlyGen | 23301498, 30379171, 32574038, ...34019948, 30059200, 35132862, 31492838, 35254053 | ||
R2571 | Methylation | score2 | IEDB PhosphoSitePlus | 27503676 | ||
R2596 | Methylation | score1 | PhosphoSitePlus | |||
R2603 | Methylation | score1 | PhosphoSitePlus | |||
R2609 | Methylation | score1 | PhosphoSitePlus | |||
S2751 | Phosphorylation | score1 | PhosphoSitePlus | |||
K2769 | Acetylation | score1 | PhosphoSitePlus | |||
K2795 | Acetylation | score1 | PhosphoSitePlus | |||
K2802 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
S2807 | Phosphorylation | score1 | PhosphoSitePlus | |||
K2809 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
S2811 | Phosphorylation | score1 | PhosphoSitePlus | |||
K2814 | Acetylation | score1 | PhosphoSitePlus | |||
K2815 | Acetylation | score1 | PhosphoSitePlus | |||
T2817 | Phosphorylation | score1 | PhosphoSitePlus | |||
K2823 | Acetylation | score1 | PhosphoSitePlus | |||
S2828 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S2831 | O-Glycosylation | score1 | GlyGen | 23301498, 30379171, 32574038, ...34019948, 30059200, 35132862, 31492838, 35254053 | ||
K2832 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
T2851 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2860 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2930 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
S2935 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S2937 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
T2942 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S2946 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S2948 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2952 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
S2977 | Phosphorylation | score1 | IEDB | 35494241 | ||
S3080 | Phosphorylation | score1 | PhosphoSitePlus | |||
K3210 | Acetylation | score1 | PhosphoSitePlus | |||
S3339 | Phosphorylation | score1 | PhosphoSitePlus | |||
T3362 | Phosphorylation | score1 | PhosphoSitePlus | |||
S3371 | Phosphorylation | score1 | PhosphoSitePlus | |||
S3519 | Phosphorylation | score1 | PhosphoSitePlus | |||
S3526 | Phosphorylation | score1 | PhosphoSitePlus | |||
T3693 | Phosphorylation | score1 | PhosphoSitePlus | |||
K3714 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
S3758 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S3786 | Phosphorylation | score1 | PhosphoSitePlus | |||
S3788 | Phosphorylation | score1 | PhosphoSitePlus | |||
S3800 | Phosphorylation | score1 | PhosphoSitePlus | |||
K3945 | Acetylation | score1 | PhosphoSitePlus | |||
S3974 | Phosphorylation | score1 | PhosphoSitePlus | |||
T3977 | Phosphorylation | score1 | PhosphoSitePlus | |||
T3997 | Phosphorylation | score1 | PhosphoSitePlus | |||
S4006 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y4018 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17081983 | ||
S4022 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17081983 | ||
K4025 | Sumoylation | score1 | PhosphoSitePlus | |||
S4034 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S4050 | Phosphorylation | score1 | PhosphoSitePlus | |||
S4071 | Phosphorylation | score1 | PhosphoSitePlus | |||
R4139 | Methylation | score1 | PhosphoSitePlus | |||
R4156 | Methylation | score1 | PhosphoSitePlus | |||
R4162 | Methylation | score1 | PhosphoSitePlus | |||
S4213 | Phosphorylation | score1 | PhosphoSitePlus | |||
K4215 | Ubiquitination | score1 | PhosphoSitePlus | |||
K4222 | Ubiquitination | score1 | PhosphoSitePlus | |||
S4260 | Phosphorylation | score1 | PhosphoSitePlus | |||
S4263 | Phosphorylation | score1 | PhosphoSitePlus | |||
S4267 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
S4274 | Phosphorylation | score1 | PhosphoSitePlus | |||
S4300 | Phosphorylation | score1 | PhosphoSitePlus | |||
S4304 | Phosphorylation | score1 | PhosphoSitePlus | |||
S4361 | Phosphorylation | score1 | PhosphoSitePlus | |||
T4370 | Phosphorylation | score1 | PhosphoSitePlus | |||
K4372 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y4526 | Phosphorylation | score1 | PhosphoSitePlus | |||
S4537 | Phosphorylation | score1 | PhosphoSitePlus | |||
S4588 | Phosphorylation | score1 | PhosphoSitePlus | |||
C4883 | Methylation | score1 | IEDB | 31844290 |
Site | PTM Type | PTM Enzyme |
Score
| Source | PMID | |
---|---|---|---|---|---|---|
S46 | Phosphorylation | score0 | HPRD | 20068231 | ||
S111 | Phosphorylation | score0 | HPRD | 18452278 | ||
S113 | Phosphorylation | score0 | HPRD | 18452278 | ||
S625 | Phosphorylation | score0 | HPRD | 18491316 | ||
S631 | Phosphorylation | score0 | HPRD | 18491316 | ||
T1219 | Phosphorylation | score0 | HPRD | 20068231 | ||
S1493 | Phosphorylation | score0 | HPRD | 18452278 | ||
T2824 | Phosphorylation | score0 | HPRD | 20068231 | ||
S2831 | Phosphorylation | score0 | HPRD | 20068231 | ||
S2930 | Phosphorylation | score0 | HPRD | 18669648 | ||
S2935 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S2937 | Phosphorylation | score0 | HPRD | 18669648 | ||
T2942 | Phosphorylation | score0 | HPRD | 18669648 | ||
S2946 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S2952 | Phosphorylation | score0 | HPRD | 18669648 | ||
S4006 | Phosphorylation | score0 | HPRD | 18452278 | ||
Y4018 | Phosphorylation | score0 | HPRD | 17081983 | ||
S4022 | Phosphorylation | score0 | HPRD | 17081983 | ||
S4034 | Phosphorylation | score0 | HPRD | 20068231, 18452278 | ||
S4227 | Phosphorylation | score0 | HPRD | 20068231 | ||
S4267 | Phosphorylation | score0 | HPRD | 20068231 | ||
S4300 | Phosphorylation | score0 | HPRD | 20068231 | ||
S4304 | Phosphorylation | score0 | HPRD | 20068231 | ||
T4388 | Phosphorylation | score0 | HPRD | 20068231 |