iPTMnet Report for Q8NEY1 (NAV1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NEY1 / NAV1_HUMAN
Protein Name Neuron navigator 1
Gene Name Name: NAV1
Synonyms:KIAA1151,KIAA1213,POMFIL3,STEERIN1;
Organism Homo sapiens (Human)

PRO ID PR:Q8NEY1
DAG View
PRO Name neuron navigator 1 (human)
Definition A neuron navigator 1 that is encoded in the genome of human.
Short Label hNAV1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NEY1 (NAV1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
K48 Acetylation PhosphoSitePlus
K58 Acetylation PhosphoSitePlus
S90 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...20068231
T92 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S95 Phosphorylation PhosphoSitePlus
S100 Phosphorylation PhosphoSitePlus
T138 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S145 Phosphorylation PhosphoSitePlus
S152 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K158 Sumoylation PhosphoSitePlus
T159 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S172 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S186 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus   UniProt 23186163
S199 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S205 Phosphorylation PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
S296 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S303 Phosphorylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
S306 Phosphorylation PhosphoSitePlus
S308 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S311 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S312 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S315 Phosphorylation phospho.ELM 18669648
S322 Phosphorylation PhosphoSitePlus
T357 Phosphorylation PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus   UniProt 20068231
S377 Phosphorylation PhosphoSitePlus
S380 Phosphorylation PhosphoSitePlus
S391 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S393 Phosphorylation PhosphoSitePlus
S440 Phosphorylation PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus
T444 Phosphorylation PhosphoSitePlus
S452 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
T453 Phosphorylation PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
S474 Phosphorylation PhosphoSitePlus   UniProt 23186163
S476 Phosphorylation PhosphoSitePlus   UniProt 23186163
K479 Ubiquitination PhosphoSitePlus
K483 Ubiquitination PhosphoSitePlus
Y486 Phosphorylation PhosphoSitePlus
S488 Phosphorylation PhosphoSitePlus
S490 Phosphorylation PhosphoSitePlus   UniProt 23186163
S507 Phosphorylation PhosphoSitePlus
S522 Phosphorylation PhosphoSitePlus
S528 Phosphorylation PhosphoSitePlus   UniProt 23186163
T534 O-Glycosylation GlyGen 28411811, 30379171, 30059200, ...35254053, 31492838, 29237092
T534 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T540 O-Glycosylation GlyGen 28411811, 30379171, 32938750, ...30059200, 35254053, 31492838, 29237092
T540 Phosphorylation phospho.ELM 18669648
S541 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T544 Phosphorylation PhosphoSitePlus   UniProt 23186163
K556 Acetylation PhosphoSitePlus
K566 Acetylation PhosphoSitePlus
K570 Acetylation PhosphoSitePlus
T572 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S579 Phosphorylation PhosphoSitePlus
S587 Phosphorylation PhosphoSitePlus
S594 Phosphorylation PhosphoSitePlus
S600 Phosphorylation PhosphoSitePlus
S604 Phosphorylation PhosphoSitePlus
T614 O-Glycosylation GlyGen 28411811, 30379171, 30059200, ...35254053, 31492838, 29237092
T627 Phosphorylation PhosphoSitePlus
S635 Phosphorylation PhosphoSitePlus
T647 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S648 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S652 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S654 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S672 Phosphorylation PhosphoSitePlus
S679 Phosphorylation PhosphoSitePlus
S680 Phosphorylation PhosphoSitePlus
S681 Phosphorylation PhosphoSitePlus
S683 Phosphorylation PhosphoSitePlus
T685 Phosphorylation PhosphoSitePlus
R688 Methylation PhosphoSitePlus
R692 Methylation PhosphoSitePlus
S697 Phosphorylation PhosphoSitePlus
S701 Phosphorylation PhosphoSitePlus
K706 Methylation PhosphoSitePlus
S723 Phosphorylation PhosphoSitePlus
T727 Phosphorylation PhosphoSitePlus
T734 Phosphorylation phospho.ELM 17081983
K744 Acetylation PhosphoSitePlus
S750 Phosphorylation PhosphoSitePlus   UniProt 19369195
S754 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K756 Ubiquitination PhosphoSitePlus
S757 O-Glycosylation GlyGen 28411811, 30379171, 30059200, ...35254053, 31492838, 29237092
S757 Phosphorylation PhosphoSitePlus
S760 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692
S763 O-Glycosylation GlyGen 28411811, 30379171, 30059200, ...35254053, 31492838, 29237092
S763 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T764 O-Glycosylation GlyGen 28411811, 30379171, 30059200, ...35254053, 31492838, 29237092
T764 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K766 Acetylation PhosphoSitePlus
S770 Phosphorylation PhosphoSitePlus
T773 Phosphorylation PhosphoSitePlus
T775 Phosphorylation PhosphoSitePlus
S791 Phosphorylation PhosphoSitePlus
S797 Phosphorylation PhosphoSitePlus   UniProt 23186163
S806 Phosphorylation PhosphoSitePlus
S808 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S884 Phosphorylation PhosphoSitePlus
S893 Phosphorylation PhosphoSitePlus
S927 Phosphorylation PhosphoSitePlus
T942 Phosphorylation PhosphoSitePlus
S954 Phosphorylation PhosphoSitePlus
S964 Phosphorylation PhosphoSitePlus
T966 Phosphorylation PhosphoSitePlus
S977 Phosphorylation PhosphoSitePlus
S981 Phosphorylation PhosphoSitePlus
T996 Phosphorylation PhosphoSitePlus
S1000 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
T1002 Phosphorylation PhosphoSitePlus
T1005 Phosphorylation PhosphoSitePlus
T1006 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S1012 Phosphorylation PhosphoSitePlus
S1014 Phosphorylation PhosphoSitePlus
T1017 Phosphorylation PhosphoSitePlus
S1035 Phosphorylation PhosphoSitePlus
S1046 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1048 Phosphorylation phospho.ELM 18669648
T1053 Phosphorylation PhosphoSitePlus
S1154 Phosphorylation PhosphoSitePlus
T1170 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1181 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1182 Phosphorylation PhosphoSitePlus
S1190 Phosphorylation PhosphoSitePlus
S1212 Phosphorylation PhosphoSitePlus
S1219 Phosphorylation PhosphoSitePlus
S1220 Phosphorylation PhosphoSitePlus
S1226 Phosphorylation PhosphoSitePlus
S1233 Phosphorylation PhosphoSitePlus
S1236 Phosphorylation PhosphoSitePlus
S1238 Phosphorylation PhosphoSitePlus
T1245 Phosphorylation PhosphoSitePlus
S1248 Phosphorylation PhosphoSitePlus
S1252 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1253 Phosphorylation PhosphoSitePlus
S1260 Phosphorylation PhosphoSitePlus
T1263 Phosphorylation PhosphoSitePlus
S1265 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S1267 Phosphorylation PhosphoSitePlus
T1281 Phosphorylation PhosphoSitePlus
T1291 Phosphorylation PhosphoSitePlus
K1317 Methylation PhosphoSitePlus
K1320 Methylation PhosphoSitePlus
S1366 Phosphorylation PhosphoSitePlus
S1369 Phosphorylation PhosphoSitePlus
T1370 Phosphorylation PhosphoSitePlus
S1381 Phosphorylation PhosphoSitePlus
S1382 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1386 Phosphorylation PhosphoSitePlus
S1405 Phosphorylation PhosphoSitePlus
S1518 Phosphorylation PhosphoSitePlus
K1709 Ubiquitination PhosphoSitePlus
T1818 Phosphorylation PhosphoSitePlus
S1823 Phosphorylation PhosphoSitePlus
S1826 Phosphorylation PhosphoSitePlus
T1832 Phosphorylation PhosphoSitePlus
S1836 Phosphorylation phospho.ELM 18669648
T1837 Phosphorylation PhosphoSitePlus
S1840 Phosphorylation PhosphoSitePlus
S1843 Phosphorylation PhosphoSitePlus
Y1859 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1862 Phosphorylation PhosphoSitePlus
T1867 Phosphorylation PhosphoSitePlus
T1876 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S90 Phosphorylation HPRD 19651622, 18669648, 19664994, ...20068231
T92 Phosphorylation HPRD 18669648
S142 Phosphorylation HPRD 19651622, 20068231
S145 Phosphorylation HPRD 19651622
S152 Phosphorylation HPRD 18669648
T159 Phosphorylation HPRD 18669648
S172 Phosphorylation HPRD 20068231
S199 Phosphorylation HPRD 19651622, 18669648, 19691289
S296 Phosphorylation HPRD 18669648
S308 Phosphorylation HPRD 19651622, 18669648, 20068231
S311 Phosphorylation HPRD 19651622, 18669648, 20068231
S312 Phosphorylation HPRD 18669648, 20068231
S315 Phosphorylation HPRD 18669648
S362 Phosphorylation HPRD 20068231
S364 Phosphorylation HPRD 20068231
S391 Phosphorylation HPRD 19413330, 18767875, 18669648, ...19415658
S452 Phosphorylation HPRD 18669648, 19691289, 20068231
S464 Phosphorylation HPRD 20068231
T497 Phosphorylation HPRD 20068231
S528 Phosphorylation HPRD 20068231
T534 Phosphorylation HPRD 18669648
T540 Phosphorylation HPRD 18669648
S541 Phosphorylation HPRD 18669648
T572 Phosphorylation HPRD 18669648
T647 Phosphorylation HPRD 18669648, 20068231
S648 Phosphorylation HPRD 18669648
S652 Phosphorylation HPRD 18669648
S654 Phosphorylation HPRD 18669648
S672 Phosphorylation HPRD 20068231
S695 Phosphorylation HPRD 20068231
S696 Phosphorylation HPRD 20068231
T726 Phosphorylation HPRD 19007248
S750 Phosphorylation HPRD 20068231
S754 Phosphorylation HPRD 18669648, 20068231
S757 Phosphorylation HPRD 19651622
S760 Phosphorylation HPRD 19413330, 19651622, 18669648, ...19691289
S763 Phosphorylation HPRD 18669648
T764 Phosphorylation HPRD 18669648, 19691289
S808 Phosphorylation HPRD 18669648, 20068231
S981 Phosphorylation HPRD 17081983, 20068231
S1000 Phosphorylation HPRD 18767875, 18669648, 20068231
T1002 Phosphorylation HPRD 19413330
T1005 Phosphorylation HPRD 20068231
T1006 Phosphorylation HPRD 18669648, 20068231
T1170 Phosphorylation HPRD 18669648, 20068231
S1181 Phosphorylation HPRD 19651622, 18669648, 20068231
S1252 Phosphorylation HPRD 18669648
S1253 Phosphorylation HPRD 19413330
S1260 Phosphorylation HPRD 20068231
T1261 Phosphorylation HPRD 20068231
S1265 Phosphorylation HPRD 19691289, 20068231
S1267 Phosphorylation HPRD 19651622
T1370 Phosphorylation HPRD 20068231
S1382 Phosphorylation HPRD 18669648, 20068231
S1386 Phosphorylation HPRD 20068231
S1405 Phosphorylation HPRD 20068231
S1823 Phosphorylation HPRD 20068231
S1836 Phosphorylation HPRD 18669648, 20068231
Y1859 Phosphorylation HPRD 18669648, 20068231
S1862 Phosphorylation HPRD 19691289
Site PTM Type PTM Enzyme Score Source PMID
S90 Phosphorylation phospho.ELM 18669648
T92 Phosphorylation phospho.ELM 18669648
S152 Phosphorylation phospho.ELM 18669648
T159 Phosphorylation phospho.ELM 18669648
S199 Phosphorylation phospho.ELM 18669648
S296 Phosphorylation phospho.ELM 18669648
S308 Phosphorylation phospho.ELM 18669648
S311 Phosphorylation phospho.ELM 18669648
S312 Phosphorylation phospho.ELM 18669648
S315 Phosphorylation phospho.ELM 18669648
S391 Phosphorylation phospho.ELM 18669648
S440 Phosphorylation PhosphoSitePlus
S443 Phosphorylation PhosphoSitePlus
T444 Phosphorylation PhosphoSitePlus
S452 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T453 Phosphorylation PhosphoSitePlus
S507 Phosphorylation PhosphoSitePlus
T534 Phosphorylation phospho.ELM 18669648
T540 Phosphorylation phospho.ELM 18669648
S541 Phosphorylation phospho.ELM 18669648
T572 Phosphorylation phospho.ELM 18669648
S594 Phosphorylation PhosphoSitePlus
S600 Phosphorylation PhosphoSitePlus
S604 Phosphorylation PhosphoSitePlus
T647 Phosphorylation phospho.ELM 18669648
S648 Phosphorylation phospho.ELM 18669648
S652 Phosphorylation phospho.ELM 18669648
S654 Phosphorylation phospho.ELM 18669648
S754 Phosphorylation phospho.ELM 18669648
S760 Phosphorylation phospho.ELM 18669648
S763 Phosphorylation phospho.ELM 18669648
T764 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S808 Phosphorylation phospho.ELM 18669648
S964 Phosphorylation PhosphoSitePlus
S1000 Phosphorylation phospho.ELM 18669648
T1006 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1046 Phosphorylation phospho.ELM 18669648
S1048 Phosphorylation phospho.ELM 18669648
Site PTM Type PTM Enzyme Score Source PMID
S24 Phosphorylation PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus
S44 Phosphorylation PhosphoSitePlus
S821 Phosphorylation PhosphoSitePlus
S825 Phosphorylation PhosphoSitePlus
S826 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S24 Y24 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K48 E48 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T138 M138 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S282 F282 Biomuta DOID:4159 / skin cancer [ cosmic ]
S288 F288 Biomuta DOID:4159 / skin cancer [ cosmic ]
S308 F308 Biomuta DOID:4159 / skin cancer [ cosmic ]
T357 P357 Biomuta DOID:1324 / lung cancer [ cosmic ]
T357 I357 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ]
S362 I362 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S393 I393 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S452 L452 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S464 * Biomuta DOID:2394 / ovarian cancer [ cosmic ]
K483 I483 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S488 G488 Biomuta DOID:363 / uterine cancer [ icgc ]
S490 N490 Biomuta DOID:363 / uterine cancer [ icgc ]
S541 F541 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S594 L594 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T614 A614 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S652 F652 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R688 Q688 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
R692 L692 Biomuta DOID:1324 / lung cancer [ cosmic ]
T734 S734 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S750 L750 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S797 L797 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S826 F826 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T942 P942 Biomuta DOID:363 / uterine cancer [ icgc ]
T996 A996 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1000 R1000 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1006 M1006 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1035 F1035 Biomuta [ cosmic ]
S1048 F1048 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T1053 M1053 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1170 A1170 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1182 L1182 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1220 F1220 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1248 C1248 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1366 L1366 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1826 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S1840 Y1840 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
Y1859 H1859 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y1859 D1859 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S1862 F1862 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T1867 I1867 Biomuta DOID:4159 / skin cancer [ cosmic ]