Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NEV4 / MYO3A_HUMAN
Protein Name Myosin-IIIa
Gene Name Name: MYO3A
Organism Homo sapiens (Human)

PRO ID PR:Q8NEV4
DAG View
PRO Name myosin-IIIa (human)
Definition A myosin-IIIa that is encoded in the genome of human.
Short Label hMYO3A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NEV4 (MYO3A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S73 Phosphorylation PhosphoSitePlus
Y82 Phosphorylation PhosphoSitePlus
Y85 Phosphorylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
T178 Phosphorylation Q8NEV4 (MYO3A) PhosphoSitePlus 24214986
T184 Phosphorylation Q8NEV4 (MYO3A) PhosphoSitePlus   RLIMS-P 24214986, 25402663
T188 Phosphorylation PhosphoSitePlus   RLIMS-P 25402663
T302 Phosphorylation PhosphoSitePlus
K399 Ubiquitination PhosphoSitePlus
Y509 Phosphorylation PhosphoSitePlus
K513 Ubiquitination PhosphoSitePlus
S688 Phosphorylation PhosphoSitePlus
T853 Phosphorylation PhosphoSitePlus
T908 Phosphorylation Q8NEV4 (MYO3A) PhosphoSitePlus 24214986
T919 Phosphorylation Q8NEV4 (MYO3A) PhosphoSitePlus 24214986
Y1125 Phosphorylation PhosphoSitePlus
S1167 Phosphorylation PhosphoSitePlus
T1279 Phosphorylation PhosphoSitePlus
S1280 Phosphorylation PhosphoSitePlus
K1306 Acetylation PhosphoSitePlus
S1355 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
Y1394 Phosphorylation PhosphoSitePlus
Y1396 Phosphorylation PhosphoSitePlus
Y1459 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y509 Phosphorylation HPRD 19562805
S1355 Phosphorylation HPRD 15302935


Q8NEV4 (MYO3A) as PTM Enzyme



Substrate Site Score Source PMID
Q8NEV4 (MYO3A) T178 PhosphoSitePlus 24214986
Q8NEV4 (MYO3A) T184 PhosphoSitePlus 24214986
Q8NEV4 (MYO3A) T908 PhosphoSitePlus 24214986
Q8NEV4 (MYO3A) T919 PhosphoSitePlus 24214986


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S73 P73 Biomuta DOID:363 / uterine cancer [ tcga ]
T184 I184 Biomuta DOID:1324 / lung cancer [ tcga ]
T302 M302 Biomuta DOID:5041 / esophageal cancer [ icgc ] DOID:11054 / urinary bladder cancer [ tcga ]
T908 S908 Biomuta DOID:1324 / lung cancer [ tcga ]
S1167 F1167 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S1280 F1280 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
K1306 E1306 Biomuta DOID:3571 / liver cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ]
Y1394 * Biomuta DOID:10534 / stomach cancer [ icgc, tcga ]