iPTMnet Report for Q8NEV4 (MYO3A)
Protein Information
| UniProt AC / UniProt ID | Q8NEV4 / MYO3A_HUMAN |
| Protein Name | Myosin-IIIa |
| Gene Name | Name: MYO3A |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8NEV4 |
| PRO Name | myosin-IIIa (human) |
| Definition | A myosin-IIIa that is encoded in the genome of human. |
| Short Label | hMYO3A |
| Category | organism-gene |
DAG ViewQ8NEV4 (MYO3A) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S73 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y82 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y85 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S177 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T178 | Phosphorylation | Q8NEV4 (MYO3A) | score2 | PhosphoSitePlus | 24214986 | |
| T184 | Phosphorylation | Q8NEV4 (MYO3A) | score4 | PhosphoSitePlus RLIMS-P | 24214986, 25402663 | |
| T188 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 25402663 | ||
| T302 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K399 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y509 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K513 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S688 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T853 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T908 | Phosphorylation | Q8NEV4 (MYO3A) | score2 | PhosphoSitePlus | 24214986 | |
| T919 | Phosphorylation | Q8NEV4 (MYO3A) | score2 | PhosphoSitePlus | 24214986 | |
| Y1125 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1167 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1279 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1280 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1306 | Acetylation | score1 | PhosphoSitePlus | |||
| S1355 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 15302935 | ||
| Y1394 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1396 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1459 | Phosphorylation | score1 | PhosphoSitePlus |
Q8NEV4 (MYO3A) as PTM Enzyme
|
Substrate | Site | Score | Source | PMID |
|---|---|---|---|---|---|
| Q8NEV4 (MYO3A) | T178 | score2 | PhosphoSitePlus | 24214986 | |
| Q8NEV4 (MYO3A) | T184 | score2 | PhosphoSitePlus | 24214986 | |
| Q8NEV4 (MYO3A) | T908 | score2 | PhosphoSitePlus | 24214986 | |
| Q8NEV4 (MYO3A) | T919 | score2 | PhosphoSitePlus | 24214986 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y85 | C85 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T178 | I178 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| T302 | M302 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
| S688 | R688 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S1167 | F1167 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S1280 | F1280 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K1306 | E1306 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S1355 | N1355 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S1355 | G1355 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| Y1394 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] |
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