iPTMnet Report for Q8NER5 (ACVR1C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NER5 / ACV1C_HUMAN
Protein Name Activin receptor type-1C precursor
Gene Name Name: ACVR1C
Synonyms:ALK7;
Organism Homo sapiens (Human)

PRO ID PR:Q8NER5
DAG View
PRO Name activin receptor type-1C (human)
Definition An activin receptor type-1C that is encoded in the genome of human.
Short Label hACVR1C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NER5 (ACVR1C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K147 Acetylation PhosphoSitePlus
K165 Acetylation PhosphoSitePlus
K168 Acetylation PhosphoSitePlus
K327 Ubiquitination PhosphoSitePlus


Q8NER5 (ACVR1C) as PTM Enzyme



Substrate Site Score Source PMID
Q15796 (SMAD2) S465 neXtProt 16709598
Q15796 (SMAD2) S467 neXtProt 16709598


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K147 N147 Biomuta DOID:363 / uterine cancer [ cosmic ]
K165 N165 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]