iPTMnet Report for Q8NEM7 (SUPT20H)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NEM7 / SP20H_HUMAN
Protein Name Transcription factor SPT20 homolog
Gene Name Name: SUPT20H
Synonyms:C13orf19,FAM48A;ORFNames:FP757;
Organism Homo sapiens (Human)

PRO ID PR:Q8NEM7
DAG View
PRO Name transcription factor SPT20 homolog (human)
Definition A transcription factor SPT20 that is encoded in the genome of human.
Short Label hSUPT20H
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NEM7 (SUPT20H) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K34 Ubiquitination PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
Y87 Phosphorylation PhosphoSitePlus
K155 Sumoylation PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
S296 Phosphorylation PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
T350 Phosphorylation PhosphoSitePlus
K351 Ubiquitination PhosphoSitePlus
T353 Phosphorylation PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
Y364 Phosphorylation PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus
S428 Phosphorylation PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus
S453 Phosphorylation PhosphoSitePlus
K457 Ubiquitination PhosphoSitePlus
S492 O-Glycosylation GlyGen 34846842, 34019948, 30379171, ...32574038, 30059200, 29351928, 35132862, 31492838, 35289036
S492 Phosphorylation PhosphoSitePlus
T494 O-Glycosylation GlyGen 34846842, 34019948, 30379171, ...32574038, 30059200, 29351928, 35132862, 31492838, 35289036
T494 Phosphorylation PhosphoSitePlus   UniProt 23186163
S498 O-Glycosylation GlyGen 34846842, 34019948, 30379171, ...32574038, 30059200, 29351928, 35132862, 31492838, 35289036
S499 O-Glycosylation GlyGen 34846842, 30379171, 32574038, ...32938750, 34019948, 30059200, 35132862, 31492838, 35289036, 29351928
S502 O-Glycosylation GlyGen 34846842, 34019948, 30379171, ...32574038, 30059200, 29351928, 35132862, 31492838, 35289036
S503 O-Glycosylation GlyGen 34846842, 34019948, 30379171, ...32574038, 30059200, 29351928, 35132862, 31492838, 35289036
S503 Phosphorylation PhosphoSitePlus
K507 Ubiquitination PhosphoSitePlus
S508 Phosphorylation PhosphoSitePlus
S509 Phosphorylation PhosphoSitePlus
S519 Phosphorylation PhosphoSitePlus   UniProt 19690332
S524 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S381 Phosphorylation HPRD 18452278
S437 Phosphorylation HPRD 19651622, 20068231, 18452278
S503 Phosphorylation HPRD 20068231
S508 Phosphorylation HPRD 20068231
S524 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S382 Phosphorylation HPRD 18452278
S438 Phosphorylation HPRD 19651622, 20068231, 18452278
S504 Phosphorylation HPRD 20068231
S509 Phosphorylation HPRD 20068231
S525 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K269 E269 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K457 N457 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S508 L508 Biomuta DOID:4159 / skin cancer [ cosmic ]
S509 L509 Biomuta DOID:4159 / skin cancer [ cosmic ]
S519 F519 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S519 C519 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]