iPTMnet Report for Q8NEM1 (ZNF680)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NEM1 / ZN680_HUMAN
Protein Name Zinc finger protein 680
Gene Name Name: ZNF680
Organism Homo sapiens (Human)

PRO ID PR:Q8NEM1
DAG View
PRO Name zinc finger protein 680 (human)
Definition A zinc finger protein 680 that is encoded in the genome of human.
Short Label hZNF680
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NEM1 (ZNF680) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K106 Ubiquitination PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
T148 Phosphorylation PhosphoSitePlus
T149 Phosphorylation PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
K152 Ubiquitination PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
Y159 Phosphorylation PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
Y210 Phosphorylation PhosphoSitePlus
K211 Sumoylation PhosphoSitePlus
K227 Acetylation PhosphoSitePlus
K236 Acetylation PhosphoSitePlus
K239 Acetylation PhosphoSitePlus
K239 Sumoylation PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
K267 Sumoylation PhosphoSitePlus
T289 Phosphorylation PhosphoSitePlus
T317 Phosphorylation PhosphoSitePlus
K323 Sumoylation PhosphoSitePlus
K342 Ubiquitination PhosphoSitePlus
T345 Phosphorylation PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
K351 Sumoylation PhosphoSitePlus
K351 Ubiquitination PhosphoSitePlus
T373 Phosphorylation PhosphoSitePlus
K379 Sumoylation PhosphoSitePlus
S390 Phosphorylation PhosphoSitePlus
T401 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
K407 Sumoylation PhosphoSitePlus
K407 Ubiquitination PhosphoSitePlus
Y434 Phosphorylation PhosphoSitePlus
Y462 Phosphorylation PhosphoSitePlus
K491 Sumoylation PhosphoSitePlus
K491 Ubiquitination PhosphoSitePlus
K497 Ubiquitination PhosphoSitePlus
T513 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T122 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T149 S149 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S151 G151 Biomuta DOID:3571 / liver cancer [ cosmic ]
K239 I239 Biomuta DOID:1324 / lung cancer [ cosmic ]
K239 T239 Biomuta DOID:363 / uterine cancer [ icgc ]
K255 Q255 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T289 I289 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K323 T323 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K342 R342 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
K342 N342 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K348 I348 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T401 P401 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y462 C462 Biomuta DOID:1324 / lung cancer [ cosmic ]