iPTMnet Report for Q8NEM0 (MCPH1)
Protein Information
UniProt AC / UniProt ID | Q8NEM0 / MCPH1_HUMAN |
Protein Name | Microcephalin |
Gene Name | Name: MCPH1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8NEM0 |
PRO Name | microcephalin (human) |
Definition | A microcephalin that is encoded in the genome of human. |
Short Label | hMCPH1 |
Category | organism-gene |
Q8NEM0 (MCPH1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K38 | Ubiquitination | score1 | PhosphoSitePlus | |||
K62 | Ubiquitination | score1 | PhosphoSitePlus | |||
S102 | Phosphorylation | score1 | PhosphoSitePlus | |||
K105 | Ubiquitination | score1 | PhosphoSitePlus | |||
K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
T120 | Phosphorylation | score1 | PhosphoSitePlus | |||
T143 | Phosphorylation | score1 | PhosphoSitePlus | |||
S191 | Phosphorylation | score1 | PhosphoSitePlus | |||
K250 | Ubiquitination | score1 | PhosphoSitePlus | |||
S254 | Phosphorylation | score1 | PhosphoSitePlus | |||
S276 | Phosphorylation | score1 | PhosphoSitePlus | |||
S277 | Phosphorylation | score1 | PhosphoSitePlus | |||
S279 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T281 | Phosphorylation | score1 | PhosphoSitePlus | |||
S287 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K297 | Ubiquitination | score1 | PhosphoSitePlus | |||
K309 | Acetylation | score1 | PhosphoSitePlus | |||
K309 | Ubiquitination | score1 | PhosphoSitePlus | |||
T312 | Phosphorylation | score1 | PhosphoSitePlus | |||
S322 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 25301947 | ||
K329 | Ubiquitination | score1 | PhosphoSitePlus | |||
S333 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus RLIMS-P UniProt | 33203878, 18669648 | ||
T335 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S337 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S338 | Phosphorylation | score1 | PhosphoSitePlus | |||
T339 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S365 | Phosphorylation | score1 | PhosphoSitePlus | |||
S406 | Phosphorylation | score1 | PhosphoSitePlus | |||
K422 | Ubiquitination | score1 | PhosphoSitePlus | |||
S437 | Phosphorylation | score1 | PhosphoSitePlus | |||
S438 | Phosphorylation | score1 | PhosphoSitePlus | |||
T543 | Phosphorylation | score1 | PhosphoSitePlus | |||
S548 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K553 | Ubiquitination | score1 | PhosphoSitePlus | |||
S623 | Phosphorylation | score1 | PhosphoSitePlus | |||
K628 | Ubiquitination | score1 | PhosphoSitePlus | |||
K632 | Ubiquitination | score1 | PhosphoSitePlus | |||
T653 | Phosphorylation | score1 | PhosphoSitePlus | |||
S657 | Phosphorylation | score1 | PhosphoSitePlus | |||
S787 | Phosphorylation | score1 | PhosphoSitePlus | |||
S794 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S276 | Phosphorylation | score0 | HPRD | 20068231 | ||
S333 | Phosphorylation | score0 | HPRD | 18669648 | ||
S337 | Phosphorylation | score0 | HPRD | 18669648 | ||
T339 | Phosphorylation | score0 | HPRD | 18669648 | ||
S548 | Phosphorylation | score0 | HPRD | 20068231 | ||
S794 | Phosphorylation | score0 | HPRD | 18452278 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T143 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y606 | Phosphorylation | score1 | PhosphoSitePlus | |||
S609 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T120 | P120 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
T143 | P143 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S191 | F191 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S254 | F254 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S333 | C333 | Biomuta | DOID:5041 / esophageal cancer [ cosmic, icgc ] | |
S437 | L437 | Biomuta | DOID:1612 / breast cancer [ icgc ] | |
K628 | E628 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] |