iPTMnet Report for Q8NEJ9 (NGDN)
Protein Information
| UniProt AC / UniProt ID | Q8NEJ9 / NGDN_HUMAN |
| Protein Name | Neuroguidin |
| Gene Name | Name: NGDN Synonyms:C14orf120; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8NEJ9 |
| PRO Name | neuroguidin (human) |
| Definition | A neuroguidin that is encoded in the genome of human. |
| Short Label | hNGDN |
| Category | organism-gene |
Q8NEJ9 (NGDN) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 19413330 | ||
| S9 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S13 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T16 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K33 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K38 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T46 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K48 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S76 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S79 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K105 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K112 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K115 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S121 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S123 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K131 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S139 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S142 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 18669648, ... | ||
| S143 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 23186163, 18669648, 15302935, ... | ||
| S168 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T184 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S202 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S204 | Phosphorylation | score2 | IEDB phospho.ELM PhosphoSitePlus UniProt | 34171305, 18669648, 23186163, ... | ||
| K210 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y213 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S214 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| S250 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S271 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S76 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S79 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S139 | Phosphorylation | score0 | HPRD | 18669648, 17081983, 20068231 | ||
| S142 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231, ... | ||
| S143 | Phosphorylation | score0 | HPRD | 17081983, 19691289, 18452278, ... | ||
| S156 | Phosphorylation | score0 | HPRD | 17081983 | ||
| S159 | Phosphorylation | score0 | HPRD | 17081983 | ||
| S202 | Phosphorylation | score0 | HPRD | 19007248, 19691289, 17081983 | ||
| S203 | Phosphorylation | score0 | HPRD | 17081983 | ||
| S204 | Phosphorylation | score0 | HPRD | 18669648, 19007248, 19691289 | ||
| Y213 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S214 | Phosphorylation | score0 | HPRD | 18669648, 19691289 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S76 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S79 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S139 | Phosphorylation | score0 | HPRD | 18669648, 17081983, 20068231 | ||
| S142 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231, ... | ||
| S143 | Phosphorylation | score0 | HPRD | 17081983, 19691289, 18452278, ... | ||
| S156 | Phosphorylation | score0 | HPRD | 17081983 | ||
| S159 | Phosphorylation | score0 | HPRD | 17081983 | ||
| S202 | Phosphorylation | score0 | HPRD | 19007248, 19691289, 17081983 | ||
| S203 | Phosphorylation | score0 | HPRD | 17081983 | ||
| S204 | Phosphorylation | score0 | HPRD | 18669648, 19007248, 19691289 | ||
| Y213 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S214 | Phosphorylation | score0 | HPRD | 18669648, 19691289 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S76 | A76 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S76 | T76 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, cosmic ] | |
| S121 | N121 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S142 | N142 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
DAG View