Protein Information

Cytoscape View

UniProt AC / UniProt ID Q8NEG7 / DEN6B_HUMAN
Protein Name Protein DENND6B
Gene Name Name: DENND6B
Organism Homo sapiens (Human)

DAG View
PRO Name protein DENND6B (human)
Definition A protein FAM116B that is encoded in the genome of human.
Short Label hDENND6B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q8NEG7 (DENND6B) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S74 Phosphorylation PhosphoSitePlus
Y115 Phosphorylation PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S117 R117 Biomuta DOID:3571 / liver cancer [ icgc ]
K378 N378 Biomuta DOID:10534 / stomach cancer [ tcga ]
S409 L409 Biomuta DOID:1324 / lung cancer [ cosmic ]