iPTMnet Report for Q8NEF3 (CCDC112)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NEF3 / CC112_HUMAN
Protein Name Coiled-coil domain-containing protein 112
Gene Name Name: CCDC112
Synonyms:MBC1;
Organism Homo sapiens (Human)

PRO ID PR:Q8NEF3
DAG View
PRO Name coiled-coil domain-containing protein 112 (human)
Definition A coiled-coil domain-containing protein 112 that is encoded in the genome of human.
Short Label hCCDC112
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NEF3 (CCDC112) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Ubiquitination PhosphoSitePlus
K13 Ubiquitination PhosphoSitePlus
K29 Ubiquitination PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
Y94 Phosphorylation PhosphoSitePlus
K102 Acetylation PhosphoSitePlus
T104 Phosphorylation PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
S287 Phosphorylation PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
K347 Acetylation PhosphoSitePlus
T409 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
Site PTM Type PTM Enzyme Score Source PMID
K78 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K209 Q209 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K209 I209 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]