iPTMnet Report for Q8NE09 (RGS22)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NE09 / RGS22_HUMAN
Protein Name Regulator of G-protein signaling 22
Gene Name Name: RGS22
Organism Homo sapiens (Human)

PRO ID PR:Q8NE09
DAG View
PRO Name regulator of G-protein signaling 22 (human)
Definition A regulator of G-protein signaling 22 that is encoded in the genome of human.
Short Label hRGS22
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NE09 (RGS22) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S377 Phosphorylation PhosphoSitePlus
T383 Phosphorylation PhosphoSitePlus
S403 Phosphorylation PhosphoSitePlus
Y460 Phosphorylation PhosphoSitePlus
Y467 Phosphorylation PhosphoSitePlus
S470 Phosphorylation PhosphoSitePlus
S599 Phosphorylation PhosphoSitePlus
S613 Phosphorylation PhosphoSitePlus
Y641 Phosphorylation PhosphoSitePlus
K852 Acetylation PhosphoSitePlus
K1000 Acetylation PhosphoSitePlus
K1001 Acetylation PhosphoSitePlus
K1173 Acetylation PhosphoSitePlus
Y1202 Phosphorylation PhosphoSitePlus
T1242 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S377 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S403 C403 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S613 P613 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1173 R1173 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]