iPTMnet Report for Q8NE01 (CNNM3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NE01 / CNNM3_HUMAN
Protein Name Metal transporter CNNM3
Gene Name Name: CNNM3
Synonyms:ACDP3;
Organism Homo sapiens (Human)

PRO ID PR:Q8NE01
DAG View
PRO Name metal transporter CNNM3 (human)
Definition A metal transporter CNNM3 that is encoded in the genome of human.
Short Label hCNNM3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NE01 (CNNM3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N73 N-Glycosylation GlyGen 24190977
S92 Phosphorylation PhosphoSitePlus
C193 Methylation IEDB 31844290
R295 Methylation PhosphoSitePlus
Y301 Phosphorylation PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
Y364 Phosphorylation PhosphoSitePlus
K407 Ubiquitination PhosphoSitePlus
K410 Ubiquitination PhosphoSitePlus
S453 Phosphorylation PhosphoSitePlus
Y456 Phosphorylation PhosphoSitePlus
T459 Phosphorylation PhosphoSitePlus
K462 Ubiquitination PhosphoSitePlus
K464 Ubiquitination PhosphoSitePlus
S467 Phosphorylation PhosphoSitePlus
K473 Ubiquitination PhosphoSitePlus
K475 Ubiquitination PhosphoSitePlus
K482 Ubiquitination PhosphoSitePlus
Y488 Phosphorylation PhosphoSitePlus
K489 Ubiquitination PhosphoSitePlus
S512 Phosphorylation PhosphoSitePlus
K519 Ubiquitination PhosphoSitePlus
K526 Ubiquitination PhosphoSitePlus
S552 Phosphorylation PhosphoSitePlus
Y557 Phosphorylation PhosphoSitePlus
S595 Phosphorylation PhosphoSitePlus
S599 Phosphorylation PhosphoSitePlus
Y624 Phosphorylation PhosphoSitePlus
K640 Ubiquitination PhosphoSitePlus
S661 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
T665 Phosphorylation PhosphoSitePlus
S673 Phosphorylation PhosphoSitePlus
T675 Phosphorylation PhosphoSitePlus
K681 Ubiquitination PhosphoSitePlus
T682 Phosphorylation PhosphoSitePlus
S688 Phosphorylation PhosphoSitePlus
S691 Phosphorylation PhosphoSitePlus
S700 Phosphorylation PhosphoSitePlus   UniProt 23186163
Site PTM Type PTM Enzyme Score Source PMID
S661 Phosphorylation HPRD 18691976, 20068231
S691 Phosphorylation HPRD 19413330
S700 Phosphorylation HPRD 19413330, 19664994, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S613 Phosphorylation HPRD 18691976, 20068231
S643 Phosphorylation HPRD 19413330
S652 Phosphorylation HPRD 19413330, 19664994, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K306 M306 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K306 L306 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
Y456 C456 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K464 N464 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y488 H488 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S552 G552 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y557 H557 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S595 * Biomuta DOID:4159 / skin cancer [ cosmic ]
Y624 * Biomuta DOID:4159 / skin cancer [ cosmic ]
T665 I665 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T665 A665 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K681 N681 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]