iPTMnet Report for Q8NE00 (TMEM104)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NE00 / TM104_HUMAN
Protein Name Transmembrane protein 104
Gene Name Name: TMEM104
Organism Homo sapiens (Human)

PRO ID PR:Q8NE00
DAG View
PRO Name transmembrane protein 104 (human)
Definition A transmembrane protein 104 that is encoded in the genome of human.
Short Label hTMEM104
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NE00 (TMEM104) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K83 Ubiquitination PhosphoSitePlus
S90 Phosphorylation PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus
T92 Phosphorylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
S96 Phosphorylation PhosphoSitePlus
Y104 Phosphorylation PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
S120 Phosphorylation PhosphoSitePlus
Y232 Phosphorylation PhosphoSitePlus
T237 Phosphorylation PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
K381 Ubiquitination PhosphoSitePlus
K460 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S90 Phosphorylation HPRD 17081983
S91 Phosphorylation HPRD 19651622, 17081983
T92 Phosphorylation HPRD 19651622, 17081983
S94 Phosphorylation HPRD 19651622, 17081983
S96 Phosphorylation HPRD 17081983
Site PTM Type PTM Enzyme Score Source PMID
K274 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T92 A92 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S94 L94 Biomuta DOID:5041 / esophageal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
Y232 C232 Biomuta DOID:363 / uterine cancer [ icgc ]