iPTMnet Report for Q8NDX1 (PSD4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NDX1 / PSD4_HUMAN
Protein Name PH and SEC7 domain-containing protein 4
Gene Name Name: PSD4
Synonyms:EFA6B;
Organism Homo sapiens (Human)

PRO ID PR:Q8NDX1
DAG View
PRO Name PH and SEC7 domain-containing protein 4 (human)
Definition A PH and SEC7 domain-containing protein 4 that is encoded in the genome of human.
Short Label hPSD4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NDX1 (PSD4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T50 Phosphorylation PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
S109 Phosphorylation PhosphoSitePlus
T114 Phosphorylation PhosphoSitePlus
S118 Phosphorylation PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus   UniProt 23186163
S134 Phosphorylation PhosphoSitePlus   UniProt 23186163
S138 Phosphorylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus   UniProt 23186163
K181 Ubiquitination PhosphoSitePlus
T230 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
T317 Phosphorylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus
T410 Phosphorylation PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus   UniProt 23186163
S448 Phosphorylation PhosphoSitePlus   UniProt 24275569
S461 Phosphorylation PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus
S465 Phosphorylation PhosphoSitePlus
S469 Phosphorylation PhosphoSitePlus
S488 Phosphorylation PhosphoSitePlus
S490 Phosphorylation PhosphoSitePlus
S491 Phosphorylation PhosphoSitePlus   UniProt 19690332
T495 Phosphorylation PhosphoSitePlus
S501 Phosphorylation PhosphoSitePlus
S502 Phosphorylation PhosphoSitePlus
T548 Phosphorylation PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus
S565 Phosphorylation PhosphoSitePlus
K586 Ubiquitination PhosphoSitePlus
K603 Ubiquitination PhosphoSitePlus
K723 Ubiquitination PhosphoSitePlus
K752 Ubiquitination PhosphoSitePlus
K761 Ubiquitination PhosphoSitePlus
S763 Phosphorylation PhosphoSitePlus
K764 Ubiquitination PhosphoSitePlus
K779 Ubiquitination PhosphoSitePlus
K786 Ubiquitination PhosphoSitePlus
T808 Phosphorylation PhosphoSitePlus
Y816 Phosphorylation PhosphoSitePlus
C825 Methylation IEDB 31844290
T854 Phosphorylation IEDB 35494241
S905 Phosphorylation PhosphoSitePlus
Y975 Phosphorylation PhosphoSitePlus
S1013 Phosphorylation PhosphoSitePlus
K1016 Ubiquitination PhosphoSitePlus
S1017 Phosphorylation PhosphoSitePlus
S1019 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1020 Phosphorylation PhosphoSitePlus
S1022 Phosphorylation PhosphoSitePlus
T1031 Phosphorylation PhosphoSitePlus
S1039 Phosphorylation PhosphoSitePlus
T1043 Phosphorylation PhosphoSitePlus
K1046 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T317 Phosphorylation HPRD 20058876
S1019 Phosphorylation HPRD 19651622


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T114 N114 Biomuta DOID:1324 / lung cancer [ cosmic ]
S134 P134 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S233 P233 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S461 C461 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S464 L464 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ]
S465 F465 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T495 M495 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S502 F502 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T548 I548 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S558 R558 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K764 N764 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
T808 A808 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T854 I854 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1019 L1019 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1020 C1020 Biomuta [ cosmic ]
S1020 R1020 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T1031 M1031 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T1043 I1043 Biomuta DOID:1319 / brain cancer [ cosmic ]