iPTMnet Report Q8NDH3 NPEPL1

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q8NDH3 / PEPL1_HUMAN
Protein Name	Probable aminopeptidase NPEPL1
Gene Name	Name: NPEPL1 Synonyms:KIAA1974;
Organism	Homo sapiens (Human)

PRO ID	PR:Q8NDH3 DAG View
PRO Name	probable aminopeptidase NPEPL1 (human)
Definition	A probable aminopeptidase NPEPL1 that is encoded in the genome of human.
Short Label	hNPEPL1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q8NDH3 (NPEPL1) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S88	Phosphorylation		score1	PhosphoSitePlus
	C189	Methylation		score1	IEDB	31844290
	K206	Ubiquitination		score1	PhosphoSitePlus
	K221	Ubiquitination		score1	PhosphoSitePlus
	Y229	Phosphorylation		score1	PhosphoSitePlus
	S270	Phosphorylation		score1	PhosphoSitePlus
	K272	Ubiquitination		score1	PhosphoSitePlus
	Y331	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T96	Phosphorylation		score0	HPRD	20068231

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
T96	M96	Biomuta		DOID:9256 / colorectal cancer [ cosmic, icgc ]
C189	R189	Biomuta		DOID:4606 / bile duct cancer [ cosmic ]
S270	G270	Biomuta		DOID:263 / kidney cancer [ cosmic ]
S270	N270	Biomuta		DOID:1612 / breast cancer [ cosmic, icgc ] DOID:2174 / ocular cancer [ tcga ]