iPTMnet Report for Q8ND82 (ZNF280C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8ND82 / Z280C_HUMAN
Protein Name Zinc finger protein 280C
Gene Name Name: ZNF280C
Synonyms:SUHW3,ZNF633;
Organism Homo sapiens (Human)

PRO ID PR:Q8ND82
DAG View
PRO Name zinc finger protein 280C (human)
Definition A zinc finger protein 280C that is encoded in the genome of human.
Short Label hZNF280C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8ND82 (ZNF280C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Sumoylation PhosphoSitePlus
K72 Sumoylation PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
K75 Sumoylation PhosphoSitePlus
S76 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S80 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...18220336
S105 Phosphorylation PhosphoSitePlus
R107 Methylation PhosphoSitePlus
S115 Phosphorylation HPRD   PhosphoSitePlus 17525332
S118 Phosphorylation HPRD   PhosphoSitePlus 17525332
T120 Phosphorylation PhosphoSitePlus
K126 Sumoylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
T130 Phosphorylation PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus
S155 Phosphorylation HPRD   PhosphoSitePlus 18077418
K167 Sumoylation PhosphoSitePlus
S170 Phosphorylation PhosphoSitePlus
K174 Methylation PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
T185 Phosphorylation PhosphoSitePlus
K187 Acetylation PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
T213 Phosphorylation PhosphoSitePlus
S215 Phosphorylation PhosphoSitePlus
S220 Phosphorylation PhosphoSitePlus
T223 Phosphorylation PhosphoSitePlus   UniProt 23186163
T225 Phosphorylation PhosphoSitePlus
S226 Phosphorylation HPRD   PhosphoSitePlus 19413330
S227 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19691289, ...20068231
Y235 Phosphorylation PhosphoSitePlus
K241 Sumoylation PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
K273 Sumoylation PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
S426 Phosphorylation PhosphoSitePlus
T455 Phosphorylation PhosphoSitePlus
K509 Ubiquitination PhosphoSitePlus
S515 Phosphorylation PhosphoSitePlus
S521 Phosphorylation PhosphoSitePlus
T540 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
T543 Phosphorylation PhosphoSitePlus
S544 Phosphorylation PhosphoSitePlus
S555 Phosphorylation PhosphoSitePlus
S560 Phosphorylation PhosphoSitePlus
K564 Ubiquitination PhosphoSitePlus
T568 Phosphorylation PhosphoSitePlus
K574 Ubiquitination PhosphoSitePlus
K604 Sumoylation PhosphoSitePlus
S606 Phosphorylation PhosphoSitePlus
K610 Ubiquitination PhosphoSitePlus
K620 Ubiquitination PhosphoSitePlus
C641 Methylation IEDB 31844290
K689 Ubiquitination PhosphoSitePlus
S697 Phosphorylation PhosphoSitePlus
T711 Phosphorylation HPRD 20068231
K723 Ubiquitination PhosphoSitePlus
S724 Phosphorylation HPRD   PhosphoSitePlus 18491316
T725 Phosphorylation HPRD   PhosphoSitePlus 18491316
T727 Phosphorylation HPRD   PhosphoSitePlus 18491316
S728 Phosphorylation HPRD   PhosphoSitePlus 18491316
K737 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K75 T75 Biomuta DOID:363 / uterine cancer [ icgc ]
S76 C76 Biomuta DOID:1324 / lung cancer [ cosmic ]
S105 L105 Biomuta [ cosmic ] DOID:1612 / breast cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:2394 / ovarian cancer [ cosmic, icgc ]
R107 G107 Biomuta DOID:4159 / skin cancer [ cosmic ]
S115 L115 Biomuta DOID:4159 / skin cancer [ cosmic ]
S118 Y118 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T120 A120 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S133 L133 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T185 N185 Biomuta DOID:1319 / brain cancer [ icgc ]
S215 F215 Biomuta [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S226 P226 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S515 L515 Biomuta DOID:4159 / skin cancer [ cosmic ]
K610 N610 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]