iPTMnet Report for Q8ND76 (CCNY)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8ND76 / CCNY_HUMAN
Protein Name Cyclin-Y
Gene Name Name: CCNY
Synonyms:C10orf9,CBCP1,CFP1;
Organism Homo sapiens (Human)

PRO ID PR:Q8ND76
DAG View
PRO Name cyclin-Y (human)
Definition A cyclin-Y that is encoded in the genome of human.
Short Label hCCNY
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8ND76 (CCNY) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 19524571, 20059949
S12 Phosphorylation PhosphoSitePlus   RLIMS-P 26205494, 28057719
S21 Phosphorylation PhosphoSitePlus   UniProt 23186163
S25 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18669648, 24794231
Y26 Phosphorylation PhosphoSitePlus
T30 Phosphorylation PhosphoSitePlus   UniProt 24794231
S33 Phosphorylation O94921 (CDK14) PhosphoSitePlus   UniProt 24794231
T37 Phosphorylation O94921 (CDK14) PhosphoSitePlus   UniProt 24794231, 24275569
S66 Phosphorylation PhosphoSitePlus
T67 Phosphorylation PhosphoSitePlus   UniProt 24794231
S71 Phosphorylation O94921 (CDK14) PhosphoSitePlus   RLIMS-P   Signor   UniProt 24794231
K72 Ubiquitination PhosphoSitePlus
S73 Phosphorylation O94921 (CDK14) PhosphoSitePlus   RLIMS-P   Signor   UniProt 24794231
T75 Phosphorylation PhosphoSitePlus   UniProt 24794231
S83 Phosphorylation PhosphoSitePlus   UniProt 24794231, 23186163
Y98 Phosphorylation IEDB   PhosphoSitePlus 35494241
S99 Phosphorylation PhosphoSitePlus   UniProt 24794231
S100 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 26205494, 28057719, 24794231
S102 Phosphorylation PhosphoSitePlus   UniProt 24794231
T103 Phosphorylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
Y237 Phosphorylation PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus   UniProt 24794231
S295 Phosphorylation PhosphoSitePlus   UniProt 24794231
K301 Ubiquitination PhosphoSitePlus
S324 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 24794231, 18669648, 32098961, ...18220336
S326 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 21406692, 18088087, 18220336, ...22184064, 28057719, 15302935, 18669648, 26205494, 24794231, 24275569, 23186163, 32098961
T331 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S336 Phosphorylation Q00536 (CDK16) PhosphoSitePlus   RLIMS-P 26205494, 28057719, 32098961
Site PTM Type PTM Enzyme Score Source PMID
S25 Phosphorylation HPRD 18669648
S73 Phosphorylation HPRD 20166139
S100 Phosphorylation HPRD 20166139
S102 Phosphorylation HPRD 19413330
S153 Phosphorylation HPRD 20068231
S324 Phosphorylation HPRD 18578522, 17081983, 18767875, ...19651622, 18669648, 20166139, 20068231
S326 Phosphorylation HPRD 19413330, 18578522, 18088087, ...15302935, 19664994, 18452278, 19651622, 18669648, 20058876, 20166139, 19415658, 20068231
T331 Phosphorylation HPRD 18578522
Site PTM Type PTM Enzyme Score Source PMID
S19 Phosphorylation HPRD 20166139
S46 Phosphorylation HPRD 20166139
S48 Phosphorylation HPRD 19413330
S99 Phosphorylation HPRD 20068231
S270 Phosphorylation HPRD 18578522, 17081983, 18767875, ...19651622, 18669648, 20166139, 20068231
S272 Phosphorylation HPRD 19413330, 18578522, 18088087, ...15302935, 19664994, 18452278, 19651622, 18669648, 20058876, 20166139, 19415658, 20068231
T277 Phosphorylation HPRD 18578522


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q8ND76 (CCNY) S326 Q00536 (CDK16) unknown eFIP 32098961


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T67 K67 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T75 M75 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S99 L99 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S153 L153 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
Y237 H237 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S295 I295 Biomuta DOID:1324 / lung cancer [ cosmic ]