Protein Information

Cytoscape View

UniProt AC / UniProt ID Q8NCW5 / NNRE_HUMAN
Protein Name NAD(P)H-hydrate epimerase precursor
Gene Name Name: NAXE
Organism Homo sapiens (Human)

DAG View
PRO Name NAD(P)H-hydrate epimerase (human)
Definition An apolipoprotein A-I-binding protein that is encoded in the genome of human.
Short Label hNAXE
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q8NCW5 (NAXE) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S24 Phosphorylation PhosphoSitePlus
T34 O-Glycosylation PhosphoSitePlus
S43 Phosphorylation neXtProt 18202122
K132 Ubiquitination PhosphoSitePlus
Y141 Phosphorylation PhosphoSitePlus
K144 Acetylation PhosphoSitePlus
K148 Acetylation PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
S247 Phosphorylation PhosphoSitePlus
T252 Phosphorylation PhosphoSitePlus
Y255 Phosphorylation PhosphoSitePlus
Y257 Phosphorylation PhosphoSitePlus
R261 Methylation PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
K270 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation PRO


PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036293 (hNAXE/iso:1/Ac:1) acM1 PRO

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
M1 I1 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S24 I24 Biomuta DOID:3571 / liver cancer [ icgc ]
S247 C247 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]
R261 C261 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]