Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NCR6 / SMIP6_HUMAN
Protein Name Sperm microtubule inner protein 6
Gene Name Name: SPMIP6
Synonyms:C9orf24,CBE1;
Organism Homo sapiens (Human)

PRO ID PR:Q8NCR6
DAG View
PRO Name spermatid-specific manchette-related protein 1 (human)
Definition A spermatid-specific manchette-related protein 1 that is encoded in the genome of human.
Short Label hSMRP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NCR6 (SPMIP6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S18 Phosphorylation PhosphoSitePlus
Y123 Phosphorylation PhosphoSitePlus
T124 Phosphorylation PhosphoSitePlus
T125 Phosphorylation PhosphoSitePlus
Y126 Phosphorylation PhosphoSitePlus
R150 Methylation PhosphoSitePlus
R153 Methylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
S170 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y73 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T124 A124 Biomuta DOID:363 / uterine cancer [ cosmic ]
R150 K150 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R153 W153 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S170 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]