Protein Information

Cytoscape View

UniProt AC / UniProt ID Q8NCJ5 / SPRY3_HUMAN
Protein Name SPRY domain-containing protein 3
Gene Name Name: SPRYD3
Organism Homo sapiens (Human)

DAG View
PRO Name SPRY domain-containing protein 3 (human)
Definition A SPRY domain-containing protein 3 that is encoded in the genome of human.
Short Label hSPRYD3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q8NCJ5 (SPRYD3) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K14 Ubiquitination PhosphoSitePlus
Y22 Phosphorylation PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
K240 Sumoylation PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus
S346 Phosphorylation PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S353 F353 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]