iPTMnet Report for Q8NCJ5 (SPRYD3)
Protein Information
| UniProt AC / UniProt ID | Q8NCJ5 / SPRY3_HUMAN |
| Protein Name | SPRY domain-containing protein 3 |
| Gene Name | Name: SPRYD3 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8NCJ5 |
| PRO Name | SPRY domain-containing protein 3 (human) |
| Definition | A SPRY domain-containing protein 3 that is encoded in the genome of human. |
| Short Label | hSPRYD3 |
| Category | organism-gene |
Q8NCJ5 (SPRYD3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K14 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y22 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K138 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K240 | Sumoylation | score1 | PhosphoSitePlus | |||
| K240 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K304 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K321 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S343 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S346 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S353 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K304 | N304 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| S353 | F353 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
DAG View